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首页> 外文期刊>Pancreatology: official journal of the International Association of Pancreatology (IAP) ... [et al.] >Predictors of vascular and gastrointestinal complications in severe acute pancreatitis.
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Predictors of vascular and gastrointestinal complications in severe acute pancreatitis.

机译：严重急性胰腺炎中血管和胃肠道并发症的预测因子。

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摘要

AIM: To determine prognostic factors for arterial injury and gastrointestinal perforation in patients with severe acute pancreatitis (AP). METHODS: A prospective cohort study was performed in 39 patients with AP whose Ranson scores were > or =3. The following parameters were assessed: Ranson score, APACHE II score, C-reactive protein (CRP) concentration on admission and on day 7, and contrast-enhanced computed tomography (CT) scans on admission (first CT) and between days 6 and 8 (second CT). The Balthazar CT severity index was calculated. RESULTS: Six patients developed seven vascular and/or gastrointestinal complications (duodenal perforations in 3 and arterial pseudoaneurysm in 4). CRP on day 7 and the CT severity indices at the second CT were significantly higher in the complication group than in the noncomplication group. A stepwise logistic regression analysis demonstrated that CRP > or =15 mg/dl on day 7 and CT severity index > or =7 at the second CT were independent risk factors (p = 0.02 and 0.04, respectively). The odds ratio for CRP > or =15 mg/dl was 23.0 and 15.7 for a CT severity index of > or =7. CONCLUSION: A persistent elevation of the CRP concentration and a high CT severity index are independent risk factors for local complications associated with AP.
机译：目的：确定重症急性胰腺炎（AP）患者的动脉损伤和胃肠道穿孔的预后因素。方法：前瞻性队列研究在39例Ranson得分≥3的AP患者中进行。评估了以下参数：入院时和第7天的Ranson评分，APACHE II评分，C反应蛋白（CRP）浓度，入院时（第一次CT）以及第6天和第8天之间的对比增强计算机断层扫描（CT）扫描（第二CT）。计算了Balthazar CT严重程度指数。结果：6例患者发生了7例血管和/或胃肠道并发症（十二指肠穿孔3例，动脉假性动脉瘤4例）。并发症组第7天的CRP和第二次CT的CT严重性指标均显着高于非并发症组。逐步逻辑回归分析表明，第7天的CRP>或= 15 mg / dl，第二次CT的CT严重度指数>或= 7是独立的危险因素（分别为p = 0.02和0.04）。 CRP≥15 mg / dl的CRP的比值比为23.0，而CT严重度指数≥7的比值比为15.7。结论：持续升高的CRP浓度和较高的CT严重度指数是与AP相关的局部并发症的独立危险因素。

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