...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Parasitology >Vesicle trafficking during sporozoite development in Plasmodium berghei: ultrastructural evidence for a novel trafficking mechanism.
【24h】

Vesicle trafficking during sporozoite development in Plasmodium berghei: ultrastructural evidence for a novel trafficking mechanism.

机译：伯氏疟原虫子孢子发育过程中的囊泡运输：一种新型运输机制的超微结构证据。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Oocysts from Anopheles stephensi mosquitoes fed on murine blood infected with Plasmodium berghei berghei, were fixed for electron microscopy 6-12 days post-feeding. Ultrastructural analysis focused on Golgi-related trafficking pathways for rhoptry and microneme formation during sporogony. A small Golgi complex of 1-3 cisternae is formed close to the spindle pole body from coated vesicles budded from the nuclear envelope which is confluent with the endoplasmic reticulum. Rhoptries begin as small spheroidal bodies apparently formed by fusion of Golgi-derived vesicles, lengthening to 3-4 microm, and increasing in number to 4 per sporozoite. Ultrastructural data indicate the presence of a novel mechanism for vesicle transport between the Golgi complex and rhoptries along a longitudinal 30 nm - thick fibre (rootlet fibre or tigelle). Filamentous links between vesicles and rootlet indicate that this is a previously undescribed vesicle transport organelle. Genesis of micronemes occurs late in bud maturation and starts as spheroidal dense-cored vesicles (pro-micronemes), transforming to their mature bottle-like shape as they move apically. Filamentous links also occur between micronemes and subpellicular microtubules, indicating that as in merozoites, micronemes are trafficked actively along these structures.
机译：在喂食后6-12天，用电镜检查固定了用感染了伯氏疟原虫的鼠血喂养的斯蒂芬按蚊蚊子的卵囊。超微结构分析的重点是孢子形成过程中与高尔基体相关的贩运途径，即变态反应和微neme的形成。一个小的1-3池高尔基复合体是由从与核内膜网汇合的核被膜中萌发的带涂层囊泡靠近纺锤极体形成的。变种开始于小球状体，显然是由高尔基体来源的囊泡融合而成，延伸至3-4微米，每个子孢子数量增加至4。超微结构数据表明在高尔基复合体和沿水平30 nm粗纤维（根状纤维或tigelle）的变种之间的小泡运输新机制的存在。囊泡和根部之间的丝状连接表明这是先前未描述的囊泡运输细胞器。微neme的发生发生在芽成熟的后期，开始于球形的密芯囊泡（pro-nemene），随着它们的顶端移动而转变成成熟的瓶状形状。在微nemes和亚膜微管之间也有丝状连接，这表明与裂殖子一样，微nemes沿这些结构活跃地被贩运。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号