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Schistosome population genetic structure: when clumping worms is not just splitting hairs

机译:血吸虫群体的遗传结构:当团聚的蠕虫不仅仅是分裂头发时

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摘要

Schistosomiasis is a major public health problem, affecting over 200 million people worldwide. Although Schistosoma mansoni has been studied rigorously in an attempt to provide a vaccine based on a number of candidate antigens, there has been a lack of complementary effort to determine the range and distribution of variation in representative molecules throughout natural populations. Here, Jason Curtis and Dennis Minchella highlight current (and suggest future) research efforts aimed at assessing genetic variation in schistosome populations, and call for a more robust consideration of schistosome population genetics.
机译:血吸虫病是一个主要的公共卫生问题,全世界有超过2亿人受到感染。尽管已经严格研究了曼氏血吸虫,以提供一种基于多种候选抗原的疫苗,但缺乏互补的努力来确定整个自然种群中代表性分子变异的范围和分布。在这里,Jason Curtis和Dennis Minchella重点介绍了旨在评估血吸虫种群遗传变异的当前(并建议未来)的研究工作,并呼吁对血吸虫种群遗传学进行更充分的考虑。

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