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首页> 外文期刊>Pediatric neurology >Intracranial pressure changes during intermittent CSF drainage.
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Intracranial pressure changes during intermittent CSF drainage.

机译：脑脊液间歇性引流期间颅内压变化。

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摘要

Premature very-low-birth-weight infants with posthemorrhagic hydrocephalus are often managed with intermittent cerebrospinal fluid drainage from a ventricular reservoir. There are little data regarding intracranial pressure changes during intermittent drainage to determine the amount and frequency of cerebrospinal fluid removal or to determine the correct resistance of future programmable shunts. The objective of this study was to determine the feasibility of using a commercially available intracranial pressure transducer to measure changes in pressure associated with this procedure. Continuous intracranial pressure was measured in three infants with a transducer placed at the time of ventricular reservoir insertion. Daily reservoir taps began 48 hours after placement and intracranial pressure was monitored for 7 days. Intracranial pressure before the initial tap was comparable to levels previously reported as normal. The daily removal of 10 cc/kg of cerebrospinal fluid was sufficient to lower intracranial pressure below baseline, however it was associated with wide swings in pressure and, in one patient, sustained negative pressure. The use of direct intracranial pressure monitoring may be useful in determining the optimal amount and frequency of cerebrospinal drainage from infants with posthemorrhagic hydrocephalus managed with a ventricular reservoir, as well as determining resistance settings of subsequent programmable shunts.
机译：患有出血后脑积水的早产超低出生体重婴儿通常需要间歇性脑室积液排出脑脊液。关于间歇性引流期间确定脑脊液清除量和频率或确定未来可编程分流器的正确阻力的有关颅内压变化的数据很少。这项研究的目的是确定使用市售颅内压力传感器来测量与此过程相关的压力变化的可行性。在三名婴儿中测量持续的颅内压，并在插入心室储库时放置一个换能器。放置后48小时开始每天水库抽水，并监测颅内压7天。初次敲击前的颅内压与以前报道的正常水平相当。每天清除10 cc / kg的脑脊液足以将颅内压降低至基线以下，但是这与压力的大幅波动以及一名患者持续的负压有关。使用直接颅内压监测可能有助于确定脑室引流后婴儿的脑室引流的最佳数量和频率，并通过心室水库进行管理，并确定后续可编程分流器的阻力设置。

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