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Call-Fleming Syndrome: Headache in a 16-Year-Old Girl

机译:卡莱姆综合征:16岁女孩的头痛

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BACKGROUND: Call-Fleming syndrome, also known as reversible cerebral vasoconstriction syndrome, is an important cause of severe headache characterized by segmental constriction of cerebral arteries in multiple vascular distributions. It is commonly described in adults, with a female predominance. PATIENT: We report a case of a 16-year-old girl with history of anxiety, attention deficit hyperactivity disorder, and migraines on several medications presenting with 2 weeks of worsening headaches. RESULTS: Cranial computed tomography was normal, but magnetic resonance imaging revealed cortical subarachnoid hemorrhage. Follow-up imaging demonstrated extensive vasoconstriction of small- to medium-sized cerebral arteries. Sertraline and methylphenidate were discontinued, and nifedipine was started. Symptoms rapidly improved, and repeat angiography at 2 months showed no vasoconstriction. CONCLUSIONS: Call-Fleming syndrome is an important cause of thunderclap headache and should be considered in the pediatric population, especially in the setting of certain medication usage and other known risk factors. (C) 2013 Elsevier Inc. All rights reserved.
机译:背景:Call-Fleming综合征,也称为可逆性脑血管收缩综合征,是严重头痛的重要原因,其特征是在多个血管分布中脑动脉节段性收缩。它通常在以女性为主的成年人中描述。病人:我们报道了一个16岁女孩的案例,该女孩有焦虑史,注意力缺陷多动障碍和几种治疗偏头痛的偏头痛,头痛持续了2周。结果:颅脑CT检查正常,但磁共振成像显示蛛网膜下腔出血。随访影像显示中小型脑动脉广泛的血管收缩。停用舍曲林和哌醋甲酯,开始硝苯地平。症状迅速改善,在2个月时重复进行血管造影未显示血管收缩。结论:Call-Fleming综合征是引起雷霆性头痛的重要原因,应在儿科人群中考虑,尤其是在某些药物使用情况和其他已知危险因素的情况下。 (C)2013 Elsevier Inc.保留所有权利。

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