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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Trends in preventive asthma medication use among children and adolescents, 1988-2008.
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Trends in preventive asthma medication use among children and adolescents, 1988-2008.

机译:1988-2008年,儿童和青少年预防性哮喘药物使用的趋势。

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OBJECTIVE: To examine trends in preventive asthma medication (PAM) use among children with current asthma in the United States from 1988 to 2008. METHODS: We performed a cross-sectional analysis of PAM use among 2499 children aged 1 to 19 years with current asthma using nationally representative data from the National Health and Nutrition Examination Survey (NHANES) during 3 time periods: 1988-1994, 1999-2002, and 2005-2008. PAMs included inhaled corticosteroids, leukotriene receptor antagonists, long-acting beta-agonists, mast-cell stabilizers, and methylxanthines. RESULTS: Among children with current asthma, there was an increase in the use of PAMs from 17.8% (SE: 3.3) in 1988-1994 to 34.9% (SE: 3.3) in 2005-2008 (P < .001 for trend). Adjusting for age, gender, race/ethnicity, and health insurance status, the odds of PAM use were higher in 2005-2008 compared with 1988-1994 (adjusted odds ratio [aOR] = 2.6; 95% confidence interval [CI]: 1.5-4.5). A multivariate analysis, combining all 3 time periods, showed lower use of PAMs among non-Hispanic black (aOR = 0.5 [95% CI: 0.4-0.7]) and Mexican American (aOR = 0.6 [95% CI: 0.4-0.9]) children compared to non-Hispanic white children. PAM use was also lower in 12 to 19 year olds compared with 1 to 5 year olds and also in children who did not have health insurance compared with those who did. CONCLUSIONS: Between 1988 and 2008, the use of PAM increased among children with current asthma. Non-Hispanic black and Mexican American children, adolescents aged 12 to 19 years, and uninsured children with current asthma had lower use of PAM.
机译:目的:调查1988年至2008年美国目前患有哮喘的儿童中预防性哮喘药物使用的趋势。方法:我们对2499名目前患有哮喘的1至19岁儿童中的PAM使用进行了横断面分析。在1988-1994年,1999-2002年和2005-2008年这3个时间段内,使用来自国家健康与营养检查调查(NHANES)的具有国家代表性的数据。 PAM包括吸入的皮质类固醇,白三烯受体拮抗剂,长效β激动剂,肥大细胞稳定剂和甲基黄嘌呤。结果:在目前患有哮喘的儿童中,PAM的使用从1988-1994年的17.8%(SE:3.3)增加到2005-2008年的34.9%(SE:3.3)(趋势P <.001)。调整年龄,性别,种族/民族和健康保险状况后,2005-2008年使用PAM的几率比1988-1994年高(调整后的优势比[aOR] = 2.6; 95%置信区间[CI]:1.5 -4.5)。结合所有三个时间段的多变量分析显示,非西班牙裔黑人(aOR = 0.5 [95%CI:0.4-0.7])和墨西哥裔美国人(aOR = 0.6 [95%CI:0.4-0.9] )的儿童与非西班牙裔白人儿童相比。与1至5岁儿童相比,在12至19岁儿童中PAM的使用率也较低,在没有健康保险的儿童中,PAM的使用也有所降低。结论:在1988年至2008年之间,当前患有哮喘的儿童中PAM的使用有所增加。非西班牙裔的黑人和墨西哥裔美国儿童,12至19岁的青少年以及当前哮喘未投保的儿童使用PAM的比例较低。

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