Pediatric drug-trial recruitment: enticement without coercion.

Tishler CL; Reiss NS

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Pediatric drug-trial recruitment: enticement without coercion.

机译：儿科药物试验募集：引诱无强迫。

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Despite federal initiatives to increase research and expand data about the effectiveness and safety of medications in children, data are still limited for this population. One of the most salient barriers to conducting pediatric clinical trials involves participant recruitment. In this article, we summarize recruitment challenges including a lack of research infrastructure, the need to properly define appropriate use of incentives and payments, and inconsistencies in the current use of payments and incentives. We also searched the Centerwatch.com and ClinicalTrials.gov databases for updated data on current practices in pediatric participant compensation/payment. We provide recommendations for tackling current barriers to recruiting and retaining children and families in clinical trials.

机译：尽管联邦政府加大了研究力度并扩大了有关儿童用药有效性和安全性的数据，但该人群的数据仍然有限。进行儿科临床试验的最大障碍之一是招募参与者。在本文中，我们总结了招聘方面的挑战，其中包括缺乏研究基础架构，需要正确定义激励和薪酬的适当用法以及当前使用的薪酬和激励方面存在的矛盾。我们还搜索了Centerwatch.com和ClinicalTrials.gov数据库，以获取有关儿科参与者补偿/付款的当前做法的最新数据。我们提供了一些建议，以解决目前在临床试验中招募和留住儿童和家庭的障碍。

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《Pediatrics: Official Publication of the American Academy of Pediatrics》 |2011年第5期|共6页
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Tishler CL; Reiss NS;
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正文语种 eng
中图分类儿科学;
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1. Pediatric drug-trial recruitment: enticement without coercion. [J] . Tishler CL, Reiss NS Pediatrics: Official Publication of the American Academy of Pediatrics . 2011,第5期

机译：儿科药物试验募集：引诱无强迫。
2. Barriers to Recruitment in Pediatric Obesity Trials: Comparing Opt-in and Opt-out Recruitment Approaches [J] . McCullough Mary Beth, Janicke David, Stough Cathleen Odar, Journal of pediatric psychology . 2017,第2期

机译：儿科肥胖试验招募的障碍：比较选择和选择退出招聘方法
3. Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3. [J] . Kim S, Prout M, Ramshaw The Journal of Immunology: Official Journal of the American Association of Immunologists . 2010,第3期

机译：前沿：在通过IL-3进行蠕虫感染期间，嗜碱性粒细胞被短暂地募集到引流淋巴结中，但是感染诱导的Th2免疫可以在没有嗜碱性粒细胞淋巴结募集或IL-3的情况下发展。
4. Patient Recruitment Workflow with and without a Patient Recruitment System [C] . Benjamin Trinczek, Britta Schulte, Bernhard Breil, MEDINFO . 2013

机译：患者招聘工作流程，没有患者招聘系统
5. Improving patient-provider communication to reduce the left-without-being seen (LWBS) rates at a pediatric emergency department. [D] . Williams, Eric T. 2017

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6. A national survey of inactive physicians in the United States of America: enticements to reentry [O] . Ethan A Jewett, Sarah E Brotherton, Holly Ruch-Ross 2011

机译：美利坚合众国不活跃医师的国家调查：重返市场的诱因
7. P75 - The role of the pediatric research nurse in ensuring successful recruitment and retention of research participants for the UBIOPRED pediatric asthma study [O] . 2014

机译：P75-儿科研究护士在确保成功招募和留住UBIOPRED儿科哮喘研究的研究人员中的作用
8. Defects in Histone H3.3 Phosphorylation and ATRX Recruitment to Misaligned Chromosomes during Mitosis Contribute to the Development of Pediatric Glioblastomas. [R] . Hinchcliffe, E. H. 2015

机译：组蛋白缺陷H3.3磷酸化和aTRX招募到有丝分裂期间错位的染色体有助于小儿胶质母细胞瘤的发展。

Pediatric drug-trial recruitment: enticement without coercion.

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