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首页> 外文期刊>Pediatrics: Official Publication of the American Academy of Pediatrics >Dietary long-chain polyunsaturated fatty acids do not influence growth of term infants: A randomized clinical trial.
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Dietary long-chain polyunsaturated fatty acids do not influence growth of term infants: A randomized clinical trial.

机译：饮食中的长链多不饱和脂肪酸不影响足月儿的生长：一项随机临床试验。

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摘要

OBJECTIVE: To determine if dietary long-chain polyunsaturated fatty acids (LCPUFA) affect the growth of formula-fed infants relative to breastfed infants. METHODS: A randomized, double-blind trial of three formula-fed groups and a parallel reference group of breastfed infants was conducted. The three treatments were a placebo (no LCPUFA), docosahexaenoic acid (DHA) supplemented, and DHA plus arachidonic acid supplemented formulas fed for 12 months. Infant weight, length, head circumference, and fatty acid status were assessed at 6, 16, 34 weeks, and 1 year of age. Anthropometrics were repeated at 2 years of age. RESULTS: There were no differences between the randomized formula groups for weight, length, or head circumference even after adjustment for gender, gestational age, and the actual age at assessment. Post hoc regressions demonstrated a small negative association between DHA status at 16 weeks of age and weight at 1 and 2 years. CONCLUSIONS: Dietary LCPUFA do not influence growth of healthy term infants to a clinically significant degree.
机译：目的：确定饮食中的长链多不饱和脂肪酸（LCPUFA）相对于母乳喂养婴儿是否影响配方奶喂养婴儿的生长。方法：进行了三个配方奶粉喂养组和一个平行参考组的母乳喂养婴儿的随机双盲试验。这三种治疗分别是安慰剂（无LCPUFA），补充二十二碳六烯酸（DHA）和DHA加花生四烯酸的配方奶粉，喂养12个月。在6、16、34周和1岁时评估婴儿的体重，身长，头围和脂肪酸状况。在2岁时重复进行人体测量。结果：即使在调整性别，胎龄和评估的实际年龄之后，体重，身长或头围的随机公式组之间也没有差异。事后回归表明，16周龄的DHA状态与1岁和2岁体重之间的负相关性很小。结论：饮食中的LCPUFA不会在临床上显着影响健康足月婴儿的生长。

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