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Insect growth inhibition,antifeedant and antifungal activity of compunds isolated/derived from Zingiber officinale Roscoe 9ginger)rhizomes

机译:姜/生姜9根茎中分离/衍生的化合物对昆虫的生长抑制,抗饲料和抗真菌活性

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Fresh rhizomes of Zingiber officinale (ginger), when subjected to steam distillation, yielded ginger oil in which curcumene was found to be the major constituent. The thermally labile zingiberene-rich fraction was obtained from its diethyl ether extract. Column chromatography of ginger oleoresin furnished a fraction from which [6J-gingerol was obtained by preparative TLC. Naturally occurring [611-dehydroshogaol was synthesised following condensation of dehydrozingerone with hexanal, whereas zingerone and 3~hydroxy~1~(4~hydroxy-3-methoXyPhenYl)butane were obtained by hydro-genation of dehydrozingerone with 10% PdJC. The structures of the compounds were established by ‘H NMR, ‘3C NMR and mass (El-MS and ES-MS) spectral analysis. The test compounds exhibited moderate insect growth regulatory (IGR) and antifeedant activity against Spilosoma obliqua, and significant antifungal activity against Rhizoctonia solani. Among the various compounds, [6]-dehydroshogaol exhibited maximum IGR activity (EC50 3.55mg ml ‘) while dehydrozingerone imparted maximum antifungal activity (EC50 86.49mg litre’).
机译:姜黄的新鲜根茎(姜)经过蒸汽蒸馏后,得到姜油,姜黄素是其中的主要成分。从其二乙醚提取物中获得了热不稳定的富含姜二烯的馏分。姜油树脂的柱色谱提供了一个馏分,可通过制备TLC从中获得[6J-姜油醇。脱氢姜油酮与己醛缩合后可合成天然的[611-脱氢樟脑醇],而脱氢姜油酮与10%PdJC加氢可制得姜油酮和3-羟基-1〜(4-羟基-3-甲氧基苯酚)丁烷。化合物的结构通过1 H NMR,3 C NMR和质谱(El-MS和ES-MS)确定。这些测试化合物表现出中等的昆虫生长调节剂(IGR)和对斜螺螺的拒食活性,以及​​对茄红枯菌的显着抗真菌活性。在各种化合物中,[6]-脱氢松果酚表现出最大的IGR活性(EC50为3.55mg / ml),而脱氢姜油酮则具有最大的抗真菌活性(EC50为86.49mg /升)。

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