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首页> 外文期刊>Philippine Journal of Veterinary Medicine >Effects of Mycotoxin-Deactivating Agent on the Growth Performance of Pigs Fed Ochratoxin and Zearalenone-Contaminated Diets
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Effects of Mycotoxin-Deactivating Agent on the Growth Performance of Pigs Fed Ochratoxin and Zearalenone-Contaminated Diets

机译：霉菌毒素灭活剂对猪O曲毒素和玉米赤霉烯酮污染日粮生长性能的影响

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Forty-eight weanling pigs were used in a feeding trial to determine the effect of different levels of mycotoxin-deactivating agent (MDA; Mycofix~(R) Plus) on the growth performance of pigs fed diets contaminated with 500 ppb ochratoxin A (OTA) and 250ppb zearalenone (ZEN). Weanling pigs were randomly assigned to six treatments: Tl-basal diet; T2-basal diet + 0.20% MDA; T3-basal diet + OTA and ZEN; T4, T5 and T6-basal diet + OTA and ZEN with 0.05, 0.10 and 0.20% MDA, respectively. Each treatment wasreplicated eight times. Pigs fed the OTA and ZEN-contaminated diets without MDA had the lowest ADG and poorest FOR. The growth performance of pigs fed OTA and ZEN-contaminated diets was significantly improved by the addition of 0.20% MDA, and was statistically similar to that of pigs fed the negative control diets with or without MDA, particularly during the starter period. The FCR of pigs was likewise improved when fed OTA and ZEN-contaminated diet with 0.05 or 0.10% MDA. The addition of MDA to the mycotoxins-contaminated diet failed to significantly influence the FCR of the growing pigs. None of the prepubertal and growing gilts fed the OTA and ZEN-contaminated diets with or without MDA developed vulvovaginatis during the feeding trial. However giltsfed OTA and ZEN-contaminated diets without MDA had small ovaries and underdeveloped uterus; histologically, they showed lesions of ovarian atrophy and regression of endometrial growth. None of these gross and microscopic changes were seen in the reproductive organs of gilts fed the negative control diets and OTA and ZEN-contaminated diets with 0.10 or 0.20% MDA. Nephrotoxicosis was observed in pigs fed the OTA and ZEN-contaminated diets with 0.05% MDA and without MDA. In conclusion, results indicate that addition of 0.20% MDA to OTA and ZEN-contaminated diets improved the ADG and FCR of young pigs. Gilts had histologically normal reproductive organs.
机译：在饲养试验中使用了48只断奶猪来确定不同水平的霉菌毒素灭活剂（MDA; Mycofix〜Plus）对饲喂受500 ppb曲霉毒素A（OTA）污染的日粮的猪的生长性能的影响和250ppb玉米赤霉烯酮（ZEN）。断奶仔猪被随机分配到六种处理方法：基础日粮; T2-基础饮食+ 0.20％MDA; T3基础饮食+ OTA和ZEN; T4，T5和T6基础饮食+ OTA和ZEN分别具有0.05、0.10和0.20％的MDA。每种处理重复八次。饲喂不含MDA的受OTA和ZEN污染的日粮的猪的ADG最低，而FOR则最差。添加0.20％MDA可以显着改善饲喂受OTA和ZEN污染的日粮的猪的生长性能，并且在统计学上与饲喂有或没有MDA的阴性对照日粮的猪相似，特别是在开始期间。当饲喂含有0.05或0.10％MDA的OTA和ZEN污染的日粮时，猪的FCR同样得到改善。在受霉菌毒素污染的日粮中添加MDA不能显着影响生长猪的FCR。在喂养试验期间，无论有没有MDA的OTA和ZEN污染的日粮，青春期前和生长中的后备母猪都没有发展出阴道阴道炎。但是，不含MDA的由金边喂养的经OTA和ZEN污染的饮食的卵巢较小，子宫发育不佳。在组织学上，它们显示出卵巢萎缩的病变和子宫内膜生长的退化。在饲喂阴性对照日粮，OTA和ZEN污染日粮中添加0.10或0.20％MDA的后备母猪的生殖器官中，未见这些总体和微观变化。在饲喂含有0.05％MDA和不含MDA的OTA和ZEN污染的日粮的猪中观察到了肾毒性。总之，结果表明，在OTA和ZEN污染的日粮中添加0.20％MDA可以改善仔猪的ADG和FCR。母猪的组织器官学上正常。

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