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首页> 外文期刊>Pharmaceutical Biology >Angiotensin-converting enzyme inhibitory activity of Viscum triflorum is host plant-dependent.
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Angiotensin-converting enzyme inhibitory activity of Viscum triflorum is host plant-dependent.

机译：三花Viscum Triflorum的血管紧张素转换酶抑制活性取决于宿主植物。

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CONTEXT: Viscum triflorum DC. (Viscaceae) is a hemiparasitic plant used in traditional medicine on Reunion Island as a remedy to treat hypertension. OBJECTIVE: The in vitro angiotensin-converting enzyme (ACE) inhibitory activity of extracts of V. triflorum and the corresponding host plant species were examined to evaluate the use as a remedy against hypertension, and to investigate whether the host plants have an influence on the activity. MATERIALS AND METHODS: Aqueous, ethanol and acetone extracts of 24 leaf samples of V. triflorum and the corresponding host plants, representing 10 plant species, were prepared. The ACE inhibitory activities of the extracts were measured by HPLC using dansyltriglycine as substrate. RESULTS AND CONCLUSION: Water extracts of Viscum samples from only two of the 10 host plants, namely Acacia heterophylla Willd. (Fabaceae) and Sophora denudata Bory (Fabaceae), showed significant inhibitory activity, >/= 50% inhibition in a concentration of 0.33 mg crude plant extract in 1 mL test solution. From the two mentioned host plant species activity was only detected in the water extract from one of the six samples of A. heterophylla. Three host species showed pronounced activity without any detection of activity in the samples of V. triflorum. The results support the traditional use provided that V. triflorum is collected from A. heterophylla or S. denudata.
机译：背景：Viscum triflorum DC。 （Viscaceae）是留尼汪岛传统医学中用作治疗高血压的半寄生植物。目的：研究了三叶草提取物和相应宿主植物的体外血管紧张素转化酶（ACE）抑制活性，以评估其作为抗高血压药的用途，并研究宿主植物是否对高血压有影响。活动。材料与方法：制备了24种三花毛豆叶片样品和相应的代表10种植物的宿主植物的水，乙醇和丙酮提取物。以丹磺酰基三甘氨酸为底物，通过HPLC测量提取物的ACE抑制活性。结果与结论：仅从10个寄主植物中的2个植物（即金合欢）中提取了香豆样品的水提物。 （Fabaceae）和Sophora denudata Bory（Fabaceae）在1 mL测试溶液中的0.33 mg粗植物提取物浓度下表现出显着的抑制活性，> / = 50％抑制。从提到的两种寄主植物物种中，仅在六种异叶农杆菌样品之一的水提取物中检测到活性。三种寄主物种显示出明显的活性，而没有检测到三叶草样品中的活性。该结果支持传统用途，前提是三叶草是从太子参或无叶葡萄球菌中收集的。

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