• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国政府科技报告 >Research Needs in Management of Obesity by Severe Caloric Restriction
【24h】

Research Needs in Management of Obesity by Severe Caloric Restriction

机译：严重热量限制治疗肥胖的研究需求

获取原文
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

During 1977-1978, seventeen basically healthy but obese adults died suddenly and unexpectedly of ventricular tachydysrhythmias associated with prolonged QT intervals and low voltages, during or shortly after completing massive, rapid, weight reduction by fasting supplemented with protein products. A cause-effect relationship could not be established between the use of such products and the deaths. In addition, the specific etiology and pathogenesis of the fatal cardiac complications could not be established on the basis of available data. This report reviews aspects of obesity, its dietary treatment, and the biological and clinical effects of starvation and severe caloric restriction, emphasizing effects on the heart as well as other organs and functional systems. Clinical and laboratory data of the 17 decedent dieters are presented along with analyses of commercially available protein products. The report also includes the views of a group of leading clinical and laboratory investigators regarding possible pathogenesis of the fatal cardiac disturbances, clinical experiences in the treatment of gross obesity by starvation and very low-calorie diets, basic laboratory studies on the effects of such regimens, and identification of critical gaps in knowledge and needed additional research. The report contains a bibliography with 266 literature citations.

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号