首页> 外国专利> n- (4-chloro-3- (5-oxo-1- (4- (trifluoromethyl) phenyl) -4,5-dihydro-1h-1,2,4-triazol-3-yl) crystalline form benzyl) pivalamide, amorphous form, crystalline compound and process for the preparation of n- (4-chloro-3- (5-oxo-1- (4- (trifluoromethyl) phenyl) -4,5-dihydro-1h) crystalline form -1,2,4-triazol-3-yl) benzyl) pivalamide

n- (4-chloro-3- (5-oxo-1- (4- (trifluoromethyl) phenyl) -4,5-dihydro-1h-1,2,4-triazol-3-yl) crystalline form benzyl) pivalamide, amorphous form, crystalline compound and process for the preparation of n- (4-chloro-3- (5-oxo-1- (4- (trifluoromethyl) phenyl) -4,5-dihydro-1h) crystalline form -1,2,4-triazol-3-yl) benzyl) pivalamide

机译：正（4-氯-3-（5-氧-1-（4-（三氟甲基）苯基）-4,5-二氢-1h-1,2,4-三唑-3-基）结晶形式苄基）新戊酰胺，无定形形式，结晶化合物和制备n-（4-氯-3-（5-氧代-1-（4-（三氟甲基）苯基）-4,5-二氢-1h）结晶形式-1的方法， 2,4-三唑-3-基）苄基）新戊酰胺

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摘要

The present patent application relates to solid-state forms of a triazolone compound that exhibit mpges-1 enzyme inhibiting activity, specifically n- (4-chloro-3- (5-oxo-1- (4- ( trifluoromethyl) phenyl) -4,5-dihydro-1h-1,2,4-triazol-3-yl) benzyl) pivalamide (compound of formula ii) and process for the preparation thereof.

机译：本专利申请涉及表现出mpges-1酶抑制活性的三唑酮化合物的固态形式，特别是n-（4-氯-3-（5-氧代-1-（4-（三氟甲基）苯基）-4） 1,5-二氢-1h-1,2,4-三唑-3-基）苄基新戊酰胺（式ii的化合物）及其制备方法。

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公开/公告号BR112017026286A2

专利类型
公开/公告日2018-09-11

原文格式PDF
申请/专利权人 GLENMARK PHARMACEUTICALS S.A.;
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申请/专利号BR20171126286
发明设计人 LAXMIKANT ATMARAM GHARAT;NAGARAJAN MUTHUKAMAN;SACHIN GAVHANE;SANDEEP BANDU KHANDAGALE;SUNIL PANDURANG NIRGUDE;SURESH MAHADEV KADAM;
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申请日2016-06-13
分类号C07D249/12;
国家 BR
入库时间 2022-08-21 12:53:35

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