首页> 外国专利> Outer membrane vesicle (OMV) vaccine comprising n. meningitidis serogroup B outer membrane proteins

Outer membrane vesicle (OMV) vaccine comprising n. meningitidis serogroup B outer membrane proteins

机译:包含n。的外膜囊泡(OMV)疫苗。脑膜炎B血清群B外膜蛋白

摘要

A composition comprising (a) Neisseria meningitidis sergroup B outer membrane vesicles (OMVs), and (b) an immunogenic component selected from other Neisseria proteins, or immunogenic fragments thereof. Component (b) preferably includes a protein from a different NmB strain from that from which the OMV of component (a) is derived. The OMVs are preferably obtained by deoxycholate extraction. Optionally, the composition may also comprise a protective antigen against other pathogens.
机译:组合物,其包含(a)脑膜炎奈瑟氏球菌B族外膜囊泡(OMV),和(b)选自其他<奈瑟氏球菌>蛋白质或其免疫原性片段的免疫原性成分。组分(b)优选包括来自与衍生出组分(a)的OMV的菌株不同的NmB菌株的蛋白质。优选通过脱氧胆酸盐提取获得OMV。任选地,该组合物还可包含针对其他病原体的保护性抗原。

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