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Solidago virga-aurea var. gigantea Miq. extract for treating and preventing bone metabolism and disease

机译:一枝黄花gigantea Miq。治疗和预防骨代谢和疾病的提取物

摘要

The present invention provides a dietary supplement containing the pharmaceutical composition, and acceptable food supplements containing the extract Solidago Virgaurea useful in the prevention and treatment of bone metabolic diseases, this. ; Solidago Virgaurea extract according to the present invention, first with 80% methanol to remove impurities from the powder leaves, stems, and roots of a Solidago Virgaurea and then washed and freeze-dried at -20 ℃ and 10 times volume of the sample weight (w / v) using a filter paper, and then the extract was extracted three times for 24 hours to obtain hayeoseo twice filtered, and concentrated in a rotary vacuum evaporator and lyophilized. ; Solidago Virgaurea extract of the present invention more rapidly induced than in food and positive control known good proliferation and differentiation of osteoblasts by complex action than by a single component in the conventional bone disease, and also in the Rat growth in the animal experiments because for increasing the bone mineral density and bone mineral content without toxic effect there is an effect that can help with the appropriate treatment and prevention of bone diseases. ; Solidago Virgaurea, methanol extract, osteoblasts, osteoclasts, bone metabolism, osteoporosis, bone disease treatment and prevention
机译:本发明提供了含有药物组合物的饮食补充剂,以及含有有用的预防和治疗骨代谢疾病的提取物Solidago Virgaurea的可接受的食物补充剂。 ;根据本发明的一枝黄花提取物,首先用80%甲醇从一枝黄花的叶子,茎和根中除去杂质,然后在-20℃和10倍体积的样品重量下洗涤并冷冻干燥( w / v)使用滤纸,然后将提取物提取3次,持续24小时,从而获得两次过滤的纤维素,并在旋转真空蒸发器中浓缩并冻干。 ;本发明的一枝黄花提取物比在食品和阳性对照中更快地被诱导,已知其通过复杂的作用比在常规骨疾病中以及在动物实验中的大鼠生长中通过复合作用具有良好的成骨细胞的增殖和分化,因为增加了骨矿物质密度和骨矿物质含量无毒性作用,可以帮助适当治疗和预防骨病。 ;一枝黄花,甲醇提取物,成骨细胞,破骨细胞,骨代谢,骨质疏松症,骨病的治疗和预防

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