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首页> 外国专利> composition, and method of stimulating an immune response in an individual, prophylactically treating a disease, ameliorating a sign or symptom associated with a disease, tumor targeting, tumor growth inhibition, and detection of a tumor

composition, and method of stimulating an immune response in an individual, prophylactically treating a disease, ameliorating a sign or symptom associated with a disease, tumor targeting, tumor growth inhibition, and detection of a tumor

机译：刺激个体的免疫应答，预防性治疗疾病，改善与疾病相关的体征或症状，靶向肿瘤，抑制肿瘤生长和检测肿瘤的组合物和方法

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COMPOSITION AND METHODS OF STIMULATING AN IMMUNE RESPONSE IN AN INDIVIDUAL, PROPHYLACTIC TREATMENT OF A DISEASE, IMPROVEMENT OF A SIGN OR SYMPTOM ASSOCIATED WITH A DISEASE, TUMOR TARGETING, CRUME DEDUCTION, AND DEVELOPMENT A TUMOR The invention provides compositions containing an antigen and a TIM bleach molecule. The invention further provides a TIM targeting molecule conjugate, for example, a TIM targeting molecule targeted to a therapeutic or diagnostic moiety. The invention further provides methods of using such compositions. In one embodiment, the invention provides a method I of stimulating an immune response in an individual by administering a composition comprising an antigen and a TIM targeting molecule in a pharmaceutically acceptable carrier. In another embodiment, the invention provides a method of stimulating an immune response in an individual by administering an antigen and TIM targeting molecule, which may be administered together in a single composition or separately.
机译：在疾病的个体，非肠道治疗中刺激免疫反应的组合物和方法，与疾病相关的体征或症状的改善，肿瘤靶向，面包屑的消除以及肿瘤的形成本发明提供了一种包含抗原的组合物和方法分子。本发明进一步提供了TIM靶向分子缀合物，例如靶向治疗或诊断部分的TIM靶向分子。本发明进一步提供了使用这种组合物的方法。在一个实施方案中，本发明提供了一种通过给予可药用载体中包含抗原和TIM靶向分子的组合物来刺激个体的免疫应答的方法I。在另一个实施方案中，本发明提供了通过施用抗原和TIM靶向分子来刺激个体的免疫应答的方法，所述抗原和TIM靶向分子可以以单一组合物一起或分开施用。

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