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Biodegradable Temperature-Sensitive Star-shaped Block Copolymer for Drug Delivery System
Biodegradable Temperature-Sensitive Star-shaped Block Copolymer for Drug Delivery System
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机译：用于药物递送系统的可生物降解的温度敏感型星形嵌段共聚物
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摘要
The present invention is constituted while having a biodegradable hydrophobic block, a poly (ethylene oxide) that is directed to a sol / gel thermally responsive showing the transition star-type block copolymer in accordance with the temperature, consist of the amorphous polyester in an aqueous solution It discloses a biodegradable star-shaped block copolymer comprising a hydrophilic block. According to the present invention with the temperature in an aqueous solution while maintaining the biodegradable sol / gel transition the looks, the linear block copolymer can form a gel at a lower concentration than when compared to polymer, drug delivery, it is advantageous to the formation of micelle system useful thermally responsive star-shaped block to provide a copolymer.
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