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INHIBITION OF THE VE-PTP PHOSPHATASE PROTECTS THE KIDNEY FROM ISCHEMIA-REPERFUSION INJURY
INHIBITION OF THE VE-PTP PHOSPHATASE PROTECTS THE KIDNEY FROM ISCHEMIA-REPERFUSION INJURY
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机译：Ve-PTP磷酸酶的抑制保护肾脏从缺血再灌注损伤免受肾脏
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摘要
This disclosure relates to inhibition of the VE-PTP phosphatase to protect the kidney from ischemia-reperfusion injury. This disclosure also relates to conditional knockout of VE-PTP to protect or improve the renal function in ischemia-reperfusion injury. This disclosure identifies VE-PTP as a promising therapeutic target for renal protection in ischemia-reperfusion injury and proposes using small molecule VE-PTP inhibitor to bestow protection in the context of acute kidney injury.
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