Raman spectroscopic measurements of beta-carotene and lycopene in human skin

机译：拉曼光谱法测定人皮肤中的β-胡萝卜素和番茄红素

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The antioxidant β-carotene and lycopene substances were detected non-invasively, in vivo in human skin using resonance Raman spectroscopy. Both substances were detected simultaneously. To distinguish between the substances, the Raman signals were excited at 488 nm and 514,5 nm simultaneously using a multiline Ar~+ laser. The application of a fiber based optical imaging system allowed the detection of β-carotene and lycopene on any skin area. The disturbance of the measurements because of non-homogeneous skin pigmentation was avoided by using a measuring area of 28 mm~2. The minimum power density for registration of the Raman signals and their optimum relation was determined. The Raman spectroscopic method is well suited for the evaluation of the efficacy of topically or systemically applied amounts of β-carotene and lycopene.

机译：使用共振拉曼光谱法在人体皮肤中在体内无创检测抗氧化剂β-胡萝卜素和番茄红素。同时检测到两种物质。为了区分这些物质，使用多线Ar〜+激光同时在488 nm和514,5 nm处激发拉曼信号。基于光纤的光学成像系统的应用允许在任何皮肤区域检测β-胡萝卜素和番茄红素。通过使用28 mm〜2的测量面积，避免了由于皮肤色素不均匀所引起的测量干扰。确定用于拉曼信号配准的最小功率密度及其最佳关系。拉曼光谱法非常适合评估局部或全身施用的β-胡萝卜素和番茄红素的功效。

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《Conference on Optical Technologies in Biophysics and Medicine V and Saratov Fall Meeting; 20031007-20031010; Saratov; RU》|2003年|P.20-24|共5页
会议地点 Saratov(RU);Saratov(RU);Saratov(RU)
作者
M.E. Darvin; I. Gerzonde; S. Ey; N.N. Brandt; H. Albrecht; S.A. Gonchukov; W. Sterry; J. Lademann;
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作者单位

Center of Experimental and Applied Cutaneous Physiology (CCP) Medical Faculty Charite, Humboldt-University, Berlin;

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原文格式 PDF
正文语种 eng
中图分类生物医学工程;
关键词
raman spectroscopy; human skin; noninvasive detection; skin antioxidants; β-carotene; lycopene;

机译：拉曼光谱;人体皮肤;无创检测;皮肤抗氧化剂;β-胡萝卜素;番茄红素;

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专利

1. In vivo Raman spectroscopic analysis of the influence of IR radiation on the carotenoid antioxidant substances beta-carotene and lycopene in the human skin. Formation of free radicals [J] . Darvin ME, Gersonde I, Albrecht H, Laser physics letters . 2007,第4期

机译：体内拉曼光谱分析红外辐射对人体皮肤中类胡萝卜素抗氧化剂物质β-胡萝卜素和番茄红素的影响。自由基的形成
2. Non-invasive in vivo determination of the carotenoids beta-carotene and lycopene concentrations in the human skin using the Raman spectroscopic method [J] . Darvin ME, Gersonde I, Meinke M, Journal of Physics, D. Applied Physics: A Europhysics Journal . 2005,第15期

机译：使用拉曼光谱法非侵入性体内测定人皮肤中类胡萝卜素β-胡萝卜素和番茄红素的浓度
3. Noninvasive detection of beta-carotene and lycopene in human skin using Raman spectroscopy [J] . Darvin ME, Gersonde I, Ey S, Laser Physics: An International Journal devoted to Theoretical and Experimental Laser Research and Application . 2004,第2期

机译：使用拉曼光谱法无创检测人皮肤中的β-胡萝卜素和番茄红素
4. Raman spectroscopic measurements of beta-carotene and lycopene in human skin [C] . M.E. Darvin, I. Gerzonde, S. Ey, Conference on optical technologies in biophysics and medicine . 2004

机译：β-胡萝卜素和人体皮肤中番茄红素的拉曼光谱测量
5. A Complete Portable and Low-cost Micro-opto-fluidic Raman Spectroscopic Measurement and Characterization System [D] . Storey, Emily E. 2019

机译：完整的便携式和低成本的微光流体拉曼光谱测量和表征系统
6. Resonance Raman Spectroscopic Evaluation of Skin Carotenoids as a Biomarker of Carotenoid Status for Human Studies [O] . Susan T. Mayne, Brenda Cartmel, Stephanie Scarmo, -1

机译：皮肤类胡萝卜素的共振拉曼光谱评估作为类胡萝卜素状态的生物标记物供人类研究
7. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to a combination of lycopene, proanthocyanidins, vitamin C, vitamin E, selenium and beta-carotene and contribution to normal collagen formation (ID 1669) and protection of the skin from UV-induced damage (ID 1669) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 [O] . Tetens Inge 2011

机译：EFsa饮食产品，营养和过敏专家组（NDa）;科学意见证实与番茄红素，原花青素，维生素C，维生素E，硒和β-胡萝卜素的组合有关的健康声称，以及对正常胶原蛋白形成的贡献（ID 1669）和保护皮肤免受紫外线引起的损害（ID 1669）根据第（EC）1924/2006号条例第13（1）条

Raman spectroscopic measurements of beta-carotene and lycopene in human skin

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