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Characterization of malaria infected red blood cells by scanning confocal laser and acoustic vector contrast microscopy

机译:通过扫描共聚焦激光和声矢量对比显微镜表征疟疾感染的红细胞

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Acoustic and optical multiple contrast microscopy has been employed in order to explore characterizable parameters of red blood cells, including cells infected by the parasite Plasmodium falciparum, in order to investigate cellular modifications caused by the infection and to identify possible detection schemes for disease monitoring. Imaging schemes were based on fluorescence, optical transmission, optical reflection, and amplitude and phase of ultrasound reflected from the cells. Contrast variations observed in acoustic microscopy, but not in optical microscopy, were tentatively ascribed to changes caused by the infection.
机译:为了探索红细胞的特征参数,包括被寄生虫恶性疟原虫感染的细胞,已经采用了声学和光学多重对比显微镜技术,以便研究由感染引起的细胞修饰并确定用于疾病监测的可能检测方案。成像方案基于荧光,光透射,光反射以及从细胞反射的超声波的振幅和相位。试探性地将在声学显微镜下观察到的对比度变化归因于感染引起的变化,而在光学显微镜下观察不到。

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