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Assessing Glycemic Control in Diabetes: From Self Monitoring of Blood Glucose to Continuous Glucose Monitoring System

机译:评估糖尿病血糖控制:从血糖到连续葡萄糖监测系统的自我监测

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The incidence of diabetes is increasing at an alarming rate. Maintaining tight glycemic control is essential to prevent microvascular and macrovascular complications as demonstrated by many studies. Current recommendation for HbAlc is less then 7% and even 6.5% in special individuals. HbAlc measurement is considered the gold standard of diabetes care and serves as a surrogate of diabetes-related complications, but it does not provide information about glycemic excursions. For these reasons, self-monitoring of blood glucose (SMBG) levels is considered an important adjunct to HbAlc measurements for achieving and maintaining glycemic control and consequently for reducing diabetes-related complications. A new method that offers us a complete investigation of glucose excursions is continuous glucose monitoring system (CGMS) that measure glucose concentration in subcutaneous interstitial fluid which can reflect changes in blood glucose concentrations reasonably quickly every 5 min throughout 72 hours (3 days). The aim of this paper was to evaluate the different methods of assessing glucose control in individuals with diabetes melli-tus and to compare themselves in order to establish the clinical relevance. We assessed the glycemic control by HbAlc, SMBG and CGMS Gold simultaneously in a number of 97 individuals with diabetes. 20 individuals have a HbAlc between 6,5 -7,4%, 33 patients between 7,5-8,4%, 15 between 8,5-9,4%, 10 between 9,5 - 10.5% and 7 persons more than 10,5%. It was observed that between HbAlc level and the period spent in glycemic values more than 180 mg/dl there is not a direct relationship as we expected. The same trend was observed in near normal glycemic status but in different way. Assessing of glycemia in diabetes is crucially important to the prevention of both acute and long - term complications. The 3 fundamental approaches to assessment, HbAlc, SMBG and CGM provide fundamentally different but complementary information.
机译:糖尿病的发生率以惊人的速度增加。保持紧张的血糖控制对于预防许多研究证明的微血管和大血管并发症至关重要。当前对HBALC的建议小于特殊人员的7%甚至6.5%。 HBALC测量被认为是糖尿病护理的黄金标准,并用作糖尿病相关并发症的替代物,但它不提供有关血糖游览的信息。出于这些原因,血糖(SMBG)水平的自我监测被认为是用于实现和维持血糖控制的HBALC测量的重要辅助,从而降低糖尿病相关的并发症。一种为我们提供完整调查葡萄糖偏移的新方法是连续血糖监测系统(CGMS),其测量皮下间质液中的葡萄糖浓度,这可以在72小时内每5分钟(3天)每5分钟反映血糖浓度的变化。本文的目的是评估评估糖尿病患者的个体葡萄糖对照的不同方法,并比较自己以建立临床相关性。我们评估了HBALC,SMBG和CGMS黄金的血糖控制,同时在糖尿病的一些97个个体中。 20个个体在6,5-7,4%之间的含量为7,5-8,4%,15例介于8,5-9,4%,10之间为9,5-10.5%和7人。超过10,5%。观察到,在HBALC水平和血糖价值中花费的时间超过180 mg / dl,我们预期的直接关系就没有直接的关系。在近似正常的血糖状态下观察到相同的趋势,但以不同的方式观察到。评估糖尿病糖尿病对预防急性和长期并发症至关重要。评估的3个基本方法,HBALC,SMBG和CGM提供根本不同但互补的信息。

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