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首页> 外文会议>European symposium of the working party on computer aided process engineering >Dynamic Modelling of Chromatographic Processes: A Systematic Procedure for Isotherms Determination
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Dynamic Modelling of Chromatographic Processes: A Systematic Procedure for Isotherms Determination

机译：色谱过程的动态建模：等温法测定的系统过程

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摘要

Due to the non-linear and dynamic nature of large-scale chromatographic processes, these processes are difficult to design. The accuracy of chromatography models is particularly dependent on the description of the relevant component isotherms. Identifying the correct isotherms, and determining the corresponding parameters, is a major obstacle. In this paper, we present a simple but efficient method for isotherm parameter estimation based upon the individual elution profiles of the components in the mixture. The approach requires minimal experimentation and yields a significant reduction both in terms of the time and the effort involved in finding the most suitable isotherm. The approach is demonstrated through a case study involving a binary mixture.
机译：由于大规模色谱过程的非线性和动态性质，这些过程难以设计。色谱模型的准确性特别取决于相关组分等温线的描述。识别正确的等温，并确定相应的参数是一个主要障碍。在本文中，我们基于混合物中的组分的各个洗脱轮廓提出了一种简单但有效的等温参数估计方法。该方法需要最小的实验，并在时间和努力中涉及找到最合适的等温线的努力产生显着减少。通过涉及二元混合物的案例研究证明了该方法。

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