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Indications for Vacuum-Assisted Wound Closure: When, Where and Why?

机译:真空辅助伤口闭合的适应症:何时,地点以及为什么?

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Vacuum-assisted wound closure relies on the application of negative pressure through an occlusive dressing. It acts by drawing the wound edges together, removing wound exudate and decreasing oedema, as well as by stimulating cell proliferation and differentiation, thus improving angiogenesis and promoting formation of granulation tissue. As this technique has become more popular over recent years, it is being applied for more and more indications. In orthopaedic surgery, it is used especially in wounds with a soft tissue defect, including exposed hardware; open fractures, especially of the lower extremities; for the fixation of skin grafts and flaps. The aim is to prevent breakdown or infection of high-risk surgical incisions; to accelerate closure of fasciotomies, and to improve the management of infected wounds. High-level evidence regarding the effectiveness of this technique and its superiority to other methods is scarce, and more studies are needed to clearly define the situations in which negative pressure wound therapy may be most useful.
机译:真空辅助伤口封闭依赖于通过闭塞式敷料施加负压。它的作用由伤口边缘拉在一起,除去伤口渗出物和减少水肿,以及通过刺激细胞增殖和分化,从而提高血管生成和促进肉芽组织的形成。由于这种技术近年来越来越受欢迎,它正在申请越来越多的迹象。在整形外科手术中,它特别用于具有软组织缺陷的伤口,包括暴露的硬件;打开骨折,尤其是下肢;用于固定皮肤移植物和襟翼。目的是防止崩溃或感染高危手术切口;加速封闭粉丝,并改善感染伤口的管理。关于这种技术的有效性及其对其他方法的优势的高级证据是稀缺的,并且需要更多的研究来清楚地确定负压伤害治疗可能最有用的情况。

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