Food components activating TRPA1

机译：食品成分激活TRPA1

获取原文

获取原文并翻译 | 示例

页面导航

摘要
著录项
相似文献
相关主题

摘要

We searched for novel agonists of TRPA1 in garlic, rnioga, galangal, black pepper, and royal jelly by the use of heterogeneously expressed cells. Mioga contained novel and more potent TRPA1 agonists than allyl isothiocyanate (AITC), most famous TRPA1 agonist from wasabi. Garlic and black pepper included both TRPA1 and TRPV1 agonists. A galangal pungent compound had strong activity to TRPA1. Specific fatty acids in royal jelly were TRPA1 active components, In animal studies Intravenous AITC and cinnamaldehyde injection caused adrenaline secretion in rats. Feeding experiments in mice with high-sucrose and high-fat diet resulted in suppression of visceral fat deposition by adding black pepper extract or piperine or cinnamaldehyde. These results suggest that food components activating TRPA1 may enhance energy metabolism or thermogenesis.

机译：我们通过使用异源表达的细胞，在大蒜，藜麦，高良姜，黑胡椒和蜂王浆中寻找TRPA1的新型激动剂。与来自芥末的最著名的TRPA1激动剂相比，Mioga含有比异硫氰酸烯丙酯（AITC）更新颖，更有效的TRPA1激动剂。大蒜和黑胡椒都包含TRPA1和TRPV1激动剂。高良姜辛辣化合物对TRPA1具有强活性。蜂王浆中的特定脂肪酸是TRPA1的活性成分。在动物研究中，静脉AITC和肉桂醛注射引起大鼠肾上腺素分泌。用高蔗糖和高脂饮食的小鼠进行的喂养实验通过加入黑胡椒提取物或胡椒碱或肉桂醛来抑制内脏脂肪沉积。这些结果表明，激活TRPA1的食品成分可能会增强能量代谢或生热作用。

著录项

来源
《Recent researches in modern medicine》|2011年|p.460-462|共3页
会议地点 Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB);Cambridge(GB)
作者
TATSUO WATANABE; YUSAKU IWASAKI; KENJI KOBATA; MANABU TANABE; KANAKO KOIZUMI; YUKIKO OKUMURA; YUKO TERADA; MASATAKA NARUKAWA;
展开▼
作者单位

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

Graduate School of Nutritional and Environmental Sciences Global COE Program University of Shizuoka 52-1 Yada, Suruga-ku, Shizuoka 422-8526 Japan;

展开▼
会议组织
原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
garlic; mioga; galangal; black pepper; royal jelly; trpa1; adrenaline; adipose tissue deposition; energy expenditure;

机译：大蒜; mioga;高良姜黑胡椒;蜂王浆; trpa1;肾上腺素脂肪组织沉积；能量消耗;

相似文献

外文文献
中文文献
专利

1. Effects of TRPA1 activation and inhibition on TRPA1 and CGRP expression in dorsal root ganglion neurons [J] . Xiao-Lei Wang, Li-Wei Cui, Zhen Liu, 中国神经再生研究（英文版） . 2019,第001期
2. Effects of Food Components That Activate TRPA1 Receptors on Mucosal Ion Transport in the Mouse Intestine [J] . Linda J. Fothergill, Brid Callaghan, Leni R. Rivera, Nutrients . 2016,第10期

机译：激活TRPA1受体的食物成分对小鼠肠粘膜离子转运的影响
3. Electrophilic Components of Diesel Exhaust Particles (DEP) Activate Transient Receptor Potential Ankyrin-1 (TRPA1): A Probable Mechanism of Acute Pulmonary Toxicity for DEP. [J] . Deering Rice CE, Romero EG, Shapiro D, Chemical research in toxicology . 2011,第6期

机译：柴油机排气颗粒（DEP）的亲电子组分激活了瞬态受体电位锚蛋白1（TRPA1）：DEP急性肺毒性的可能机制。
4. Galangal Pungent Component, 1'-Acetoxychavicol Acetate, Activates TRPA1 [J] . Masataka Narukawa, Kanako Koizumi, Yusaku Iwasaki Bioscience, Biotechnology, and Biochemistry . 2010,第8期

机译：高良姜辛辣成分1'-乙酰氧查韦尔乙酸酯，激活TRPA1
5. Food components activating TRPA1 [C] . TATSUO WATANABE, YUSAKU IWASAKI, KENJI KOBATA, International Conference on Medical Physiology . 2011

机译：食物组件激活TRPA1
6. A Multi-species Model for Selective Pruritus via the Direct Activation of TRPA1 [D] . Esancy, Kali Paige. 2020

机译：通过TRPA1直接激活选择性瘙痒的多种模型
7. Effects of Food Components That Activate TRPA1 Receptors on Mucosal Ion Transport in the Mouse Intestine [O] . Linda J. Fothergill, Brid Callaghan, Leni R. Rivera, 2016

机译：激活TRPA1受体的食物成分对小鼠肠道粘膜离子转运的影响
8. Effects of food components that activate TRPA1 receptors on mucosal ion transport in the Mouse intestine [O] . Fothergill, Linda J., Callaghan, Brid, Rivera, Leni R., 2016

机译：激活TRPA1受体的食品成分对小鼠肠粘膜离子转运的影响
9. Effect of Activation Policies on Accession and Continuation in the Army Reserve Components: The Annualized Reserve Component Activation Cost of Leaving Model [R] . Doyle, C. 2008

机译：激活政策对陆军后备役部队加入和延续的影响：离职模型的年化后备部件激活成本

Food components activating TRPA1

摘要

著录项

相似文献

相关主题

期刊订阅