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Prevalence of Mutant Dihydrofolate Reductase Gene (DHFR) and Its Implication on Pyrimethamine Resistance in Rural Kwara State, Nigeria

机译：突变二氢脱液还原酶基因（DHFR）的患病率及其对尼日利亚农村克瓦拉州嘧嘧啶抗性的影响

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作者
Adebobola, Obaniyi Kehinde.;
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作者单位

Kwara State University (Nigeria).;

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授予单位 Kwara State University (Nigeria).;
学科
学位 M.S.
年度 2021
页码 89 p.
总页数 89
原文格式 PDF
正文语种 eng
中图分类
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1. Polymorphisms in the dihydrofolate reductase (DHFR) and dihydropteroate synthetase (DHPS) genes of Plasmodium falciparum and in vivo resistance to sulphadoxine/pyrimethamine in isolates from Tanzania. [J] . Jelinek T, Ronn AM, Lemnge MM, Tropical Medicine and International Health: TM and IH . 1998,第8期

机译：恶性疟原虫二氢叶酸还原酶（DHFR）和二氢蝶呤合成酶（DHPS）基因的多态性以及坦桑尼亚分离物中对磺胺多辛/乙胺嘧啶的体内抗性。
2. High prevalence of dihydrofolate reductase gene mutations in Plasmodium falciparum parasites among pregnant women in Nigeria after reported use of sulfadoxine-pyrimethamine [J] . Ojurongbe Olusola, Nguetse Christian N., Fayemiwo Samuel A., Pathogens and global health . 2018,第2期

机译：据报道，尼日利亚孕妇术后亚苯甲酸亚吡喃胺患者中孕妇疟原虫寄生虫疟原虫中的二氢酚醛还原酶基因突变高
3. Short report: high prevalence and imbalanced age distribution of the Plasmodium falciparum dihydrofolate reductase gene Asn108 mutation in an area of low pyrimethamine usage in Nigeria. [J] . Mockenhaupt FP, May J, Eggelte TA, The American Journal of Tropical Medicine and Hygiene . 1999,第3期

机译：简短报告：在尼日利亚乙胺嘧啶使用率低的地区，恶性疟原虫二氢叶酸还原酶基因Asn108突变的高患病率和年龄分布不均。
4. Protection From High Dose Chemotherapy By Transduced With Double-Mutant Dihydrofolate Reductase-Cytidine Deaminase Genes Into Mice bone marrow cells [C] . World congress on breast diseases . 2008

机译：通过用双突变二氢酚酸还原酶 - 胞苷脱氨酶基因转导入高剂量化疗，进入小鼠骨髓细胞
5. Effects of Rural Youth Migration on Food Security of Rural Farming Households in Kwara State, Nigeria [D] . Nofiu, Nofiu Babatunde 2019

机译：农村青年迁移对尼日利亚克瓦拉州农村农户食品安全的影响
6. High prevalence of dihydrofolate reductase gene mutations in Plasmodium falciparum parasites among pregnant women in Nigeria after reported use of sulfadoxine-pyrimethamine [O] . Olusola Ojurongbe, Christian N. Nguetse, Samuel A. Fayemiwo, 2018

机译：据报道使用磺胺多辛-乙胺嘧啶后尼日利亚孕妇恶性疟原虫中的二氢叶酸还原酶基因突变高发生
7. SHORT REPORT: HIGH PREVALENCE AND IMBALANCED AGE DISTRIBUTION OF THE PLASMODIUM FALCIPARUM DIHYDROFOLATE REDUCTASE GENE ASN108 MUTATION IN AN AREA OF LOW PYRIMETHAMINE USAGE IN NIGERIA [O] . Frank P. Mockenhaupt, Ju Rgen May, Teunis A. Eggelte, 2015

机译：短期报告：尼日利亚低嘧啶胺区域中恶性疟原虫还原酶基因asN108突变的高患病率和不平衡年龄分布
8. Effects of Point Mutations in Plasmodium falciparum Dihydrofolate Reductase and Dihydropterate Synthase Genes on Clinical Outcomes and In Vitro Susceptibility to Sulfadoxine and Pyrimethamine [R] . 2009

机译：恶性疟原虫二氢叶酸还原酶和二氢合成酶合成酶基因点突变对磺胺多辛和乙胺嘧啶的临床疗效和体外易感性的影响

Prevalence of Mutant Dihydrofolate Reductase Gene (DHFR) and Its Implication on Pyrimethamine Resistance in Rural Kwara State, Nigeria

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