Objective: To evaluate the clinical significance of low ligation of inferior mesenteric artery (IMA) and lymph nodes dissection on radical resection for rectal cancer. Methods: 124 patients who were diagnosed rectal cancer in our hospital from June 2002 to June 2010 were randomly divided into control group (60 cases) and observation group (64 cases). The observation group was treated with low ligation of IMA and lymph nodes dissection, the control group was cured by high ligation of IMA and lymph nodes dissection After 3 years and 5 years, we followed up on 93 cases and 110 cases. The IMA lymph nodes metastasis, cancer relapse rate, 3-year survival rate and 5-year survival rate, complication rate were compared and analyzed. Results: The control group of lymph node metastasis, recurrence rates were significantly higher than those of the observation group, there were significant differences (P＜0.05); the observation group was significantly higher on survival rate of the two groups (P＜0.05); there was no significant difference on the complication of two groups (P＞0.05).Conclusion: Low ligation of IMA and lymph nodes dissection in the treatment of rectal cancer is better than high ligation of IMA and lymph nodes dissection, which should be widely applied.%目的:探讨肠系膜下动脉(IMA)低位结扎及根部淋巴结廓清对直肠癌根治术的临床意义.方法:对我院2002年6月～2010年6月收治的124例直肠癌患者进行回顾性分析.124例患者根据患病情况随机分为对照组(60例)和观察组(64例).观察组采用IMA低位结扎及根部淋巴结廓清;对照组采用IMA高位结扎术及根部淋巴结廓清,治疗后3年随访93例,5年后随访110例,比较两组IMA根部淋巴结转移率、直肠癌复发率、3年生存率和5年生存率、并发症发生率,并进行统计分析.结果:对照组的淋巴转移率、复发率均明显高于观察组,两组比较,差异有统计学意义(P＜0.05);观察组的生存率明显高于对照组,两组比较,差异有统计学意义(P＜0.05);两组并发症比较,差异无统计学意义(P＞0.05).结论:IMA低位结扎及根部淋巴结廓清对直肠癌的治疗效果优于IMA高位结扎及根部淋巴结廓清,值得推广应用.
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