目的：研究腰硬联合加氯胺酮麻醉在儿童手术中的临床效果。方法：选取遂川县妇幼保健院（以下简称“我院”）80例择期手术的儿童患者，采用随机抽签法分为氯胺酮麻醉组（对照组）和腰硬联合加氯胺酮组（观察组）各40例，观察2组患者麻醉效果。结果：2组患儿麻醉后的各生命指标均维持在正常状态。2组患儿麻醉后的平均动脉压、心率及脉搏血氧饱和度比较，差异无统计学意义（P＞0�05）；观察组患儿氯胺酮使用量明显低于对照组，差异有统计学意义（P＜0�05）；观察组患儿术后清醒时间明显短于对照组，差异有统计学意义（P＜0�05）；观察组不良反应发生率为17�50％（7／40），对照组为77�50％（31／40），差异有统计学意义（P＜0�05）。结论：应用腰硬联合加氯胺酮麻醉在儿童手术中的麻醉效果、安全性较好。%OBJECTIVE:To evaluate the clinical efficacy of combined spinal⁃epidural anesthesia plus ketamine in pediatric surgery. METHODS: A total of 80 children undergoing selective surgery in Suichuan County Maternity and Child Care Hospital ( hereinafter referred to as “our hospital”) were analyzed retrospectively, with 40 assigned to ketamine anesthesia group ( control group) and 40 combined spinal⁃epidural anesthesia plus ketamine group ( observation group). RESULTS:The life indicators in both groups maintained at a normal state. No statistically significant differences were noted in mean arterial pressure,heart rate and pulse oxygen saturation between 2 groups(P>0�05);however, there were significant differences between the two groups in total dose of ketamine(P<0�05) and in the postoperative recovery time( P<0�05 ); the incidence of adverse reactions was 17�50%( 7/40 ) in the observation group as compared with 77�50%(31/40)in the control group(P<0�05). CONCLUSIONS: Combined spinal⁃epidural anesthesia plus ketamine showed better anesthetic efficacy and less advers reactions in pediatric surgery than ketamine alone.
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