Objective To study the effect of esmolol combined with amiodarone in preventing perioperative sympathetic storms in patients with acute myocardial infarction, and to provide reference for clinical prevention and treatment. Methods 60 cases of patients who underwent coronary intervention from May 2014 to April 2017 were selected as subjects. All the patients were divided into control group and study group according to the random number table method, 30 cases in each group. All the patients were received electric cardioversion, defibrillation and other conventional treatment. In the control group, patients were treated with intravenous infusion of amiodarone on the basis of conventional therapy, and the patients in the study group were treated with esmolol on the basis of the control group. The changes of blood pressure, heart rate, cardiac function and compli-cation were compared between the two groups before and after treatment. Results There was no significant difference in blood pressure and heart rate between the two groups before treatment. After treatment, the diastolic blood pressure, systolic blood pressure and heart rate were lower in the two groups than those in the control group, the difference was statistically significant. There was no significant difference in SV and LVEF between the two groups before treatment. After treatment, the levels of SV and LVEF in the two groups were higher than those in the control group, and the difference was statistically significant. After treatment, the overall incidence of complications in the study group was 3.3% (1/30) lower than that in the control group (26.7%, 8/30), the difference was statistically significant. Conclusion Acute myocardial infarction in patients with percutaneous coro-nary intervention, the timely implementation of cardioversion, defibrillation and application of esmolol, amiodarone treatment, can effectively prevent the occurrence of sympathetic storms, reduce postoperative complications, worthy of clinical promotion.%目的:研究艾司洛尔联合胺碘酮预防急性心肌梗死冠脉介入围术期交感风暴的应用效果,为临床防治提供参考依据.方法:选取2014年5月~2017年4月期间在我院接受冠脉介入治疗,围术期通过心电图、心电监护证实出现交感风暴的60例患者作为研究对象,根据随机数表法分为对照组、研究组,各30例.两组患者均接受电复律、除颤等常规治疗,同时对照组患者在常规治疗基础上静脉滴注胺碘酮,研究组患者在对照组治疗基础上加用艾司洛尔进行治疗.比较两组患者用药前后血压水平、心率水平、心功能指标变化及并发症发生率.结果:治疗前,两组血压及心率水平差异无统计学意义;治疗后,两组患者的舒张压、收缩压、心率水平均低于用药前,且研究组低于对照组,差异有统计学意义;治疗前,两组SV、LVEF指标差异无统计学意义;治疗后,两组患者的SV、LVEF水平均高于用药前,且研究组高于对照组,差异有统计学意义;治疗后,研究组患者并发症总发生率3.3% (1/30)低于对照组的26.7%(8/30),差异有统计学意义.结论:在急性心肌梗死患者冠脉介入治疗围术期,及时实施电复律、除颤联合应用艾司洛尔、胺碘酮治疗,能有效预防交感风暴发生,减少术后并发症,值得临床实践推广.
展开▼
