目的：通过Meta分析对紫杉醇＋顺铂（ TP）与吉西他滨＋顺铂（ GP）化疗方案对肺癌抗肿瘤药物治疗患者骨髓抑制的影响进行系统分析，探讨TP和GP的骨髓抑制差别。方法通过荟萃分析对TP与GP的骨髓抑制研究进行同质性检验和合并效应量的估计。结果同质性检验：χ2＝91．84，自由度为29，P＜0．00001；合并效应量的估计：OR合并＝1．36，OR合并95％可信限为0．90～2．04。 OR合并的检验Z＝1．482．41，P＝0．14。结论 TP与GP化疗时对患者的骨髓抑制不良反应情况没有本质区别。%Objectives To compare arrest of bone marrow on different chemo-treatment methods for lung cancer by systems anal-ysis,then investigate which method is the best .Methods The arrest of bone marrow of versus were meta-analyzed using homogeneity test and combined effect test .Results Homogeneity test showed that the cited studies were homogeneous with χ2 =91.84, df=29 and P<0.00001;and by combined test , the combined OR was 1.36(95%confidence interval =0.90~2.04, Z=1.482.41,P=0.14.Conclusions There is no difference between paclitaxel combined with cisplatin and gemzar combined with cisplatin essential -ly.
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