首页> 中文期刊> 《检验医学与临床》 >辅助生殖技术在生殖中的应用及对胚胎移植效率的影响

辅助生殖技术在生殖中的应用及对胚胎移植效率的影响

         

摘要

Objective To investigate the application of assisted reproductive technology in reproduction and its effect on the efficiency of embryo transfer.Methods A total of 300 cases assisted reproductive treatment in the reproductive center of the hospital from July 2015 to July 2016 were selected as the research subject,and were randomly divided into control group(n=150)and observation group(n=150)by digital table method.In the control group,the embryo transfer was completed during the cleavage stage,and the observation group was treated with embryo transfer and fertilization.The efficiency of embryo transfer,clinical pregnancy rate,multiple pregnancy rate and abortion rate were compared between the two groups.Results There was no sig-nificant difference in the number of eggs obtained between the two groups(P>0.05);the incidence of abor-tion rate and moderate or severe ovarian hyperstimulation syndrome in the observation group was lower than that of the control group(P<0.05).There was no significant difference in the clinical pregnancy rate between the two groups(P>0.05);the efficiency and birth rate of the observation group were higher than that of the control group(P<0.05);the rate of ectopic pregnancy in the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05);there was no significant difference in the number of births and monozygotic twins between the two groups(P>0.05).Conclusion The use of as-sisted reproductive technology in reproduction can obtain higher sperm quality.It can improve embryo transfer on the basis of maintaining high clinical pregnancy rate,which is worthy of clinical application.%目的 探讨辅助生殖技术在生殖中的应用及对胚胎移植效率的影响.方法 选取2015年7月至2016年7月该院生殖中心收治的辅助生殖患者300例作为研究对象,采用随机数字表法分为对照组和观察组,每组各150例.对照组在卵裂期完成胚胎移植,观察组进行胚胎移植受精,比较两组胚胎移植效率、临床妊娠率、多胎妊娠率及流产率情况.结果 两组获卵数比较差异无统计学意义(P>0.05);观察组流产率及中重度卵巢过度刺激综合征发生率低于对照组,差异有统计学意义(P<0.05);两组临床妊娠率比较,差异无统计学意义(P>0.05);观察组胚胎种植效率、新生儿出生率高于对照组,差异有统计学意义(P<0.05);观察组异位妊娠率低于对照组,差异有统计学意义(P<0.05);两组出生男、女例数及单卵双胎率比较,差异无统计学意义(P>0.05).结论 在生殖中采用辅助生殖技术能获得更高的精子质量,在保持较高临床妊娠率的基础上能提高胚胎移植,值得临床推广应用.

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