慢性乙型肝炎病毒（HBV）感染是严重危害我国人民健康的重大传染病，而造成慢性化的免疫学机制一直是相关研究的热点。我们主要围绕T淋巴细胞和自然杀伤（NK）细胞在慢性HBV感染中作用的最新研究进展进行综述，以进一步加深细胞免疫在HBV感染中作用的认识，为慢性HBV感染的诊治提供新的思路。%Chronic infection caused by hepatitis B virus (HBV)is a serious infectious disease to threaten health in our country.The immunological mechanism of the chronicity has been the focus.The paper summarizes the development of the roles of T lymphocytes and natural killer(NK)cells in chronic infection of HBV,in order to help with developing insights into the cellular immune in chronic infection of HBV and to provide a new thought to diagnose and treat the chronic infection of HBV.
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