目的：对比不同药物对于白内障围手术期干眼症的临床治疗效果。方法选取69例白内障围手术期患有干眼症的患者，按随机数字表法分为三组，每组23例，分别采用聚丙烯酸、聚乙二醇及玻璃酸钠方法对患者的干眼症进行治疗，并观察干眼症状、泪液分泌及泪膜破裂时间等相关指标。结果聚乙二醇组及玻璃酸钠组的干眼症状评分显著低于聚丙烯酸组，泪液分泌及泪膜破裂时间显著高于聚丙烯酸组，玻璃酸钠组的泪膜破裂时间显著高于聚乙二醇组。结论玻璃酸钠对于白内障围手术期干眼症的整体治疗效果好于聚乙二醇及聚丙烯酸，该结果可作为临床治疗中的给药依据。%Objective To contrast the clinical efficacy of different drugs on dry eyes caused by cataract in perioperative period. Methods 69 patients with dry eyes caused by cataract in perioperative period were randomly divided into three groups, and treated on the dry eyes with polyacrylic acid, polyethylene glycol, and sodium hyaluronate distinctively. To observe the relevant indicators, included the symptom of dry eyes, the secretion of tears, the break-up time of lacrimal film. Results The dry eyes symptom scores of polyethylene glycol group, and sodium hyaluronate group were lower than the polyacrylic acid group, the secretion of tears, the break-up time of lacrimal film were higher than the polyacrylic acid group. The break-up time of the sodium hyaluronate group were higher than the polyethylene glycol group. Conclusion The clinical efficacy of dry eyes caused by cataract in perioperative period of sodium hyaluronate were better than the polyacrylic acid and polyethylene glycol, the results could be the theory of clinical drug delivery.
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