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DCCP and DICP: Construction and Analyses of Databases for Copper- and Iron-Chelating Proteins

机译:DCCP和DICP:铜和铁螯合蛋白数据库的构建和分析

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摘要

Copper and iron play important roles in a variety of biological processes, especially when being chelated with proteins. The proteins involved in the metal binding, transporting and metabolism have aroused much interest. To facilitate the study on this topic, we constructed two databases (DCCP and DICP) containing the known copper- and iron-chelating proteins, which are freely available from the website . Users can conveniently search and browse all of the entries in the databases. Based on the two databases, bioinformatic analyses were performed, which provided some novel insights into metalloproteins.
机译:铜和铁在各种生物过程中都起着重要作用,尤其是与蛋白质螯合时。与金属结合,转运和代谢有关的蛋白质引起了人们的极大兴趣。为便于对此主题的研究,我们构建了两个数据库(DCCP和DICP),其中包含已知的铜螯合蛋白和铁螯合蛋白,可从网站上免费获得。用户可以方便地搜索和浏览数据库中的所有条目。基于这两个数据库,进行了生物信息学分析,为金属蛋白提供了一些新颖的见解。

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