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Primary liver carcinoid tumour with a Zollinger Ellison syndrome - an unusual diagnosis: a case report

机译:患有Zollinger Ellison综合征的原发性肝类癌-异常诊断:一例报告

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摘要

Carcinoids are neuroendocrine tumours which may secrete hormones like gastrin, insulin, ACTH, etc. Liver is a common site for metastasis of carcinoid origin and an unusual site for a primary carcinoid tumour to arise.We present the case of a 51-year-old Caucasian man with diarrhoea, weight loss, duodenum ulcers and a liver mass in ultrasonography. A primary hepatic carcinoid tumour with a Zollinger Ellison syndrome was diagnosed. Surgery resection was performed and the patient remained free of symptoms two years after, with normalisation of gastrin levels.Primary hepatic carcinoid tumour represents an uncommon diagnosis, based on radiological and pathological features. The exclusion of different primary locations is necessary. Once associated with a Zollinger Ellison syndrome, diagnose may be more complicated and challenging since only 7 cases of hepatic carcinoids with gastrin secretion were reported in medical literature.A review of medical literature is performed and diagnoses tools that should be used for an accurate diagnosis and available treatment approaches are commented here.
机译:类癌是神经内分泌肿瘤,可能分泌胃泌素,胰岛素,促肾上腺皮质激素等激素。肝脏是类癌起源转移的常见部位,也是原发性类癌发生的罕见部位。我们介绍了一个51岁的病例高加索人腹泻,体重减轻,十二指肠溃疡和超声检查中的肝脏肿块。诊断出患有Zollinger Ellison综合征的原发性肝类癌。进行了手术切除,两年后患者无症状,胃泌素水平恢复正常。基于放射学和病理学特征,原发性肝类癌代表了罕见的诊断。必须排除不同的主要位置。一旦与Zollinger Ellison综合征相关联,诊断可能会变得更加复杂和具有挑战性,因为医学文献中仅报告了7例伴有胃泌素分泌的肝类癌。对医学文献进行了回顾,并诊断了应用于准确诊断和诊断的工具此处评论了可用的治疗方法。

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