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Primary liver carcinoid tumour with a Zollinger Ellison syndrome - an unusual diagnosis: a case report

机译:患有Zollinger Ellison综合征的原发性肝类癌-异常诊断:一例报告

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Carcinoids are neuroendocrine tumours which may secrete hormones like gastrin, insulin, ACTH, etc. Liver is a common site for metastasis of carcinoid origin and an unusual site for a primary carcinoid tumour to arise. We present the case of a 51-year-old Caucasian man with diarrhoea, weight loss, duodenum ulcers and a liver mass in ultrasonography. A primary hepatic carcinoid tumour with a Zollinger Ellison syndrome was diagnosed. Surgery resection was performed and the patient remained free of symptoms two years after, with normalisation of gastrin levels. Primary hepatic carcinoid tumour represents an uncommon diagnosis, based on radiological and pathological features. The exclusion of different primary locations is necessary. Once associated with a Zollinger Ellison syndrome, diagnose may be more complicated and challenging since only 7 cases of hepatic carcinoids with gastrin secretion were reported in medical literature. A review of medical literature is performed and diagnoses tools that should be used for an accurate diagnosis and available treatment approaches are commented here.
机译:类癌是神经内分泌肿瘤,可能分泌诸如胃泌素,胰岛素,促肾上腺皮质激素等激素。肝脏是类癌起源转移的常见部位,也是原发性类癌发生的罕见部位。我们在超声检查中发现一名51岁的白人男子,腹泻,体重减轻,十二指肠溃疡和肝脏肿块。诊断出患有Zollinger Ellison综合征的原发性肝类癌。进行了手术切除,两年后患者的症状消失,胃泌素水平恢复正常。基于放射学和病理学特征,原发性肝类癌肿瘤代表罕见的诊断。必须排除不同的主要位置。一旦与Zollinger Ellison综合征相关联,由于医学文献中仅报告了7例伴有胃泌素分泌的肝类癌,因此诊断可能更加复杂且具有挑战性。进行了医学文献的回顾,并在此评论了应用于准确诊断的诊断工具和可用的治疗方法。

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