• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>AIDS Research and Human Retroviruses >Subtype B Was the Dominant Strain Among HIV Type 1 Infections Except for the Population of Men Who Have Sex with Men in Harbin City China
【2h】

Subtype B Was the Dominant Strain Among HIV Type 1 Infections Except for the Population of Men Who Have Sex with Men in Harbin City China

机译：在中国哈尔滨市除男男性接触者人群外B亚型是艾滋病毒1型感染中的主要菌株。

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

We sought to identify the prevalent subtypes and study the genetic variation of HIV-1 circulating in HIV infections in Harbin City, China. Forty-seven samples from the env V3-V4 region were successfully sequenced and analyzed, which involved thirty-one men who have sex with men (MSM), eight heterosexuals, seven former plasma donors (FPD)/blood transfusion recipients (BT), and one injection drug user (IDU). In all, 46.8% of CRF01_AE, 40.4% of subtype B, and 12.8% of CRF07_BC were identified. CRF01_AE (64.5%) was the dominant strain in MSM, and subtype B (81.2%) was the chief strain in other infected subjects except for the MSM population. Among all the genotypes, the B subtype possesses greater diversity of the tetramer on the tip of V3 loop than CRF07_BC and CRF01_AE, in which the peculiar GWGR was commonly found. Because nationwide there is a trend toward the increasing presence of CRF01_AE, a consecutive surveillance campaign was necessary among all HIV vulnerable populations in this locality.
机译：我们试图鉴定流行的亚型，并研究中国哈尔滨市HIV感染者中传播的HIV-1的遗传变异。成功地对来自env V3-V4区域的47个样本进行了测序和分析，其中包括31名与男性发生性行为的男性（MSM），8名异性恋者，7名前血浆供体（FPD）/输血受者（BT），一名注射毒品使用者（IDU）。总共鉴定出46.8％的CRF01_AE，B的40.4％和CRF07_BC的12.8％。 CRF01_AE（64.5％）是MSM的主要菌株，而B型（81.2％）是MSM人群以外的其他感染对象的主要菌株。在所有基因型中，B亚型在V3环末端具有比CRF07_BC和CRF01_AE大的四聚体多样性，在CRF07_BC和CRF01_AE中通常发现特有的GWGR。由于在全国范围内，CRF01_AE的存在呈上升趋势，因此必须对该地区的所有HIV易感人群进行连续的监视运动。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号