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首页> 美国卫生研究院文献>EFSA Journal >EFSA statement on the review of the risks related to the exposure to the food additive titanium dioxide (E 171) performed by the French Agency for Food Environmental and Occupational Health and Safety (ANSES)
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EFSA statement on the review of the risks related to the exposure to the food additive titanium dioxide (E 171) performed by the French Agency for Food Environmental and Occupational Health and Safety (ANSES)

机译：EFSA关于由法国食品环境与职业健康与安全局（ANSES）进行的与食品添加剂二氧化钛（E 171）暴露相关的风险审查的声明

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On 15 April 2019, the French Agency for Food, Environmental and Occupational Health and Safety (ANSES) published an opinion on the risks related to the exposure to the food additive titanium dioxide (E 171) taking into account the most recent scientific studies available. Further to this publication, EFSA was requested by the European Commission to provide urgent scientific and technical assistance regarding the opinion issued by ANSES. In the ANSES opinion, 25 new relevant publications published between 2017 and 2019 were reviewed together with previous opinions by EFSA and ANSES and a systematic review on genotoxicity of nano titanium dioxide. In this statement, EFSA concludes that the ANSES opinion published in April 2019 does not identify any major new findings that would overrule the conclusions made in the previous two scientific opinions on the safety of titanium dioxide (E 171) as a food additive issued by the EFSA ANS Panel in 2016 and 2018. The ANSES opinion reiterates the previously identified uncertainties and data gaps, which are currently being addressed in the context of the follow‐up activities originating from the previous EFSA evaluations and their recommendations. In addition to the aspects for which the follow‐up work is currently ongoing, ANSES recommends further investigation of genotoxicity. EFSA considers this recommendation should be revisited once the ongoing work on the physico‐chemical characterisation of the food additive titanium dioxide (E 171) is completed.
机译：2019年4月15日，法国食品，环境与职业健康与安全局（ANSES）考虑到最新的科学研究对与食品添加剂二氧化钛（E 171）暴露相关的风险发表了意见。除本出版物外，欧洲委员会还要求欧洲食品安全局（EFSA）提供有关ANSES所发表意见的紧急科学和技术援助。在ANSES的意见中，EFSA和ANSES审查了2017年至2019年出版的25篇新的相关出版物以及先前的意见，并对纳米二氧化钛的遗传毒性进行了系统的审查。在此声明中，EFSA得出结论认为，2019年4月发布的ANSES意见并未发现任何重大新发现，这些新发现将推翻前两项关于二氧化钛（E 171）作为食品添加剂的安全性的科学观点得出的结论。 EFSA ANS小组于2016年和2018年提出.ANSES意见重申了先前确定的不确定性和数据缺口，目前正在根据先前EFSA评估及其建议开展的后续活动解决这些问题。除了当前正在进行的后续工作之外，ANSES还建议进一步研究遗传毒性。欧洲食品安全局认为，一旦完成食品添加剂二氧化钛的物理化学表征工作（E 171），就应重新考虑该建议。

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