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首页> 外文期刊>The Chinese-German Journal of Clinical Oncology >Percutaneous Microwave Coagulation Therapy for Patients with Primary and Metastatic Hepatic Tumors
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Percutaneous Microwave Coagulation Therapy for Patients with Primary and Metastatic Hepatic Tumors

机译：经皮微波凝集治疗原发性和转移性肝肿瘤

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Objective: To evaluate the efficacy and safety of percutaneous microwave coagulation therapy (PMCT) for patients with primary and metastatic hepatic tumors. Methods: The enrolled 100 patients with 186 tumor nodules who underwent PMCT included 79 cases of primary or recurrent liver cancers and 21 cases of metastatic liver cancer. The tumors were divided into two groups according to the tumor size in diameter: group A, 0.5 cm- < 3 cm; group B, ≥ 3 cm- < 5 cm. Under local and/or epidural anesthesia, a single percutaneous microwave antenna (or two antennas array applicator) was inserted directly into the tumor in the liver for thermo-coagulation with the aid of ultrasound guidance. Results: Among the 186 lesions in 100 patients with primary and metastatic liver cancers, in group A , 123 (66%) were coagulated once. A Follow-up of 6-12 months demonstrated that 112 lesions (91%) showed no local recurrence by CT or MRI; In group B, of the 63 lesions (33.87%) coagulated twice, 31 (49%) showed no local recurrence by CT or MRI during a follow-up of 6 months. There were no serious clinical side effects or complications in all the PMCT patients. Conclusion: PMCT gives satisfactory curative effect on tumors with < 3 cm in size. It is partly effective on lesions ≥ 3 cm- < 5 cm in size. It is a minimally invasive and effective therapy, can be used safely in the field of percutaneous hepatis surgery, and carried out even in patients with poor liver function.
机译：目的：评估经皮微波凝固疗法（PMCT）对原发性和转移性肝肿瘤患者的疗效和安全性。方法：纳入100例行PMCT的186例肿瘤结节患者，包括79例原发性或复发性肝癌和21例转移性肝癌。根据肿瘤直径大小将肿瘤分为两组：A组，0.5cm- ＜3cm； A组，0.5cm- ＜3cm； A组：0.5cm- ＜3cm。 B组，≥3 cm- <5 cm。在局麻和/或硬膜外麻醉下，将单个经皮微波天线（或两个天线阵列敷贴器）直接插入肝脏肿瘤中，以借助超声引导进行热凝。结果：A组100例原发性和转移性肝癌患者的186个病变中，123例（66％）被凝固一次。 6-12个月的随访表明，CT或MRI显示112处病灶（91％）未见局部复发。在B组中，凝血63次（33.87％）两次凝固，其中31个（49％）在6个月的随访中未显示CT或MRI局部复发。所有PMCT患者均无严重的临床副作用或并发症。结论：PMCT对3 cm以下的肿瘤具有令人满意的疗效。对于大小≥3 cm- <5 cm的病变，部分有效。这是一种微创有效的疗法，可以安全地用于经皮肝炎手术领域，甚至可以在肝功能不佳的患者中进行。

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