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首页> 外文期刊>Indian journal of public health. >Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal
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Glucose-6-phosphate dehydrogenase screening of babies born in a tertiary care hospital in West Bengal

机译：西孟加拉邦三级医院出生的婴儿的6-磷酸葡萄糖脱氢酶筛查

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摘要

About 400 million individuals worldwide have been affected by the inherited disorder of glucose-6-phosphate dehydrogenase (G6PD) deficiency that predisposes individuals to neonatal jaundice or hemolytic crisis due to drugs or infections. A descriptive observational study with longitudinal design was undertaken among 109 live newborns, delivered in labor room of IPGME and R, Kolkata during the period from June to August 2009. An objective of the study was to estimate the occurrence of G6PD deficiency among newborns and its association with different socio-demographic, clinical and gestational characteristics. 14.68% newborns were found G6PD deficient. This occurrence was not significantly related to gender, religion and ethnicity, consanguineous marriage of the parents, gestational age and birth weight of the baby. Development of severe jaundice (total serum bilirubin 15 mg/dl) was found 23.8% among G6PD deficient babies and 12.5% among non-G6PD deficient. This difference was statistically not significant.
机译：全球约有4亿人受到遗传性6磷酸葡萄糖脱氢酶（G6PD）缺乏症的影响，这种疾病使个人容易因药物或感染而发生新生儿黄疸或溶血性疾病。 2009年6月至2009年8月，在IPGME和R，分娩室分娩的109例活新生儿中，进行了纵向设计的描述性观察性研究。该研究的目的是评估新生儿及其婴儿中G6PD缺乏症的发生情况。与不同的社会人口统计学，临床和妊娠特征相关联。发现14.68％的新生儿缺乏G6PD。这种情况与性别，宗教和种族，父母的近亲结婚，婴儿的胎龄和出生体重无关。发现G6PD缺陷婴儿严重黄疸（总血清胆红素> 15 mg / dl）的发生率为23.8％，非G6PD缺陷婴儿为12.5％。这种差异在统计学上不显着。

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