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首页> 外文期刊>International Journal of General Medicine >Community-acquired pneumonia caused by carbapenem-resistant Streptococcus pneumoniae: re-examining its prevention and treatment
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Community-acquired pneumonia caused by carbapenem-resistant Streptococcus pneumoniae: re-examining its prevention and treatment

机译：耐碳青霉烯类肺炎链球菌引起的社区获得性肺炎：重新检查其预防和治疗

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Abstract: A 73-year-old man with no significant past medical history or any history of health care visits was hospitalized for pneumonia. Sputum culture revealed multidrug-resistant Streptococcus pneumoniae, even to carbapenems. The patient was later treated successfully with levofloxacin. Throat cultures from his two grandchildren revealed S. pneumoniae with the same susceptibility pattern. Analysis for resistant genes revealed gPRSP (pbp1a + pbp2x + pbp2b gene variants) in both the patient and his grandchildren, none of whom had received pneumococcal vaccines of any kind. This case illustrates the importance of the emergence of carbapenem-resistant S. pneumoniae. Non-rational use of carbapenems for community-acquired infections may be counterproductive. This case also highlights the importance of pneumococcal vaccinations in children and the elderly.
机译：摘要：一名73岁无明显病史或任何医疗保健史的男子因肺炎住院治疗。痰培养显示对肺炎链球菌有多重耐药性的肺炎链球菌。该患者后来用左氧氟沙星成功治疗。他的两个孙子的喉咙文化显示出肺炎链球菌具有相同的易感性模式。对耐药基因的分析显示，患者及其孙子均患有gPRSP（pbp1a + pbp2x + pbp2b基因变体），他们均未接种任何肺炎球菌疫苗。该病例说明了对碳青霉烯耐药的肺炎链球菌的出现的重要性。不合理使用碳青霉烯类药物治疗社区获得性感染可能会适得其反。该病例还突出了儿童和老年人肺炎球菌疫苗接种的重要性。

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