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首页> 外文期刊>Iranian journal of psychiatry. >Sleep Quality and Its Correlates in HIV Positive Patients Who Are Candidates for Initiation of Antiretroviral Therapy
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Sleep Quality and Its Correlates in HIV Positive Patients Who Are Candidates for Initiation of Antiretroviral Therapy

机译：HIV阳性患者中开始抗逆转录病毒治疗的睡眠质量及其相关性

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ObjectiveBased on Pittsburg Sleep Quality Index, it has been reported that most human immunodeficiency virus (HIV) positive patients suffer from various degrees of sleep problems. Sleep disorders can affect quality of life, physical and social functioning and can also cause chronic fatigue. Some psychological and physiological factors are related to sleep quality. The purpose of the present study was to evaluate sleep quality and its related psychological and physiological factors in Iranian human immunodeficiency virus positive patients who were candidates for initiation of antiretroviral therapy.MethodThis was a cross- sectional study of 59 HIV positive out-patients in stages 2 or 3 of HIV disease who were candidates for initiation of antiretroviral therapy. Pittsburg Sleep Quality Index (PSQI), Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HARS) and Somatization Subscale of Symptom Checklist 90 (SCL-90) were used to assess the patients’ sleep quality, depression, anxiety and physiological factors, respectively. SPSS software version 12 was used for data analysis. The Pearson correlation coefficient was utilized to analyze the correlation between PSQI and other quantitative variables.ResultsBased on the sleep quality assessment, 47.5 % of the patients had PSQI > 5 that was defined as sleep disturbances. A significant correlation was found between sleep quality and HDRS (r = 0.531, p = 0.0001), HARS (r = 0.627, p = 0.0001) and somatization subscale of SCL-90 (r = 0.36, p = 0.05).ConclusionThis study showed that human immunodeficiency virus positive individuals suffer from sleep disorders at least as same as the general population, and that psychological variables including depression and anxiety and physiological variables including physical morbidities in different systems of the body lead to sleep disturbance in this population.
机译：目的基于匹兹堡睡眠质量指数，据报道，大多数人类免疫缺陷病毒（HIV）阳性患者患有各种程度的睡眠问题。睡眠障碍会影响生活质量，身体和社交功能，还可能导致慢性疲劳。一些心理和生理因素与睡眠质量有关。这项研究的目的是评估伊朗人免疫缺陷病毒阳性患者中开始抗逆转录病毒疗法的睡眠质量及其相关的心理和生理因素。方法这是对59例HIV阳性门诊患者分阶段进行的横断面研究接受抗逆转录病毒治疗的HIV疾病中的2或3。使用匹兹堡睡眠质量指数（PSQI），汉密尔顿抑郁量表（HDRS），汉密尔顿焦虑量表（HARS）和症状检查表90的躯体化子量表（SCL-90）来评估患者的睡眠质量，抑郁，焦虑和生理状况因素。使用SPSS软件版本12进行数据分析。结果采用Pearson相关系数分析了PSQI与其他定量变量之间的相关性。结果根据睡眠质量评估，有47.5％的患者PSQI> 5，被定义为睡眠障碍。研究发现睡眠质量与HDRS（r = 0.531，p = 0.0001），HARS（r = 0.627，p = 0.0001）与SCL-90躯体化量表之间存在显着相关性（r = 0.36，p = 0.05）。人类免疫缺陷病毒阳性患者至少与普通人群一样患有睡眠障碍，并且身体不同系统中的心理变量（包括抑郁症和焦虑症）以及生理变量（包括身体疾病）会导致该人群的睡眠障碍。

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