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Green factories: plastids for the production offoreign proteins at high levels

机译：绿色工厂：用于高水平生产外源蛋白质的质体

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The soaring costs along with the increasing demand of recombinant proteins in different walks of life have fuelled the quest to find out alternate modes for their production, which are cheaper, safer and can deliver the modern safety standards. In this context, plants are emerging as an alternative production platform for foreign proteins. Chloroplasts – the green plastids with an in-built remarkable capacity to express foreign proteins at high levels – offer several attractive features, which make plants an exceptionally useful system for low-cost production of high- value targets at large scale. Transformation of chloroplasts, therefore, holds a great potential to meet the challenges in the areas of food, feed and medicine posed by a population on the rise. Numerous developments have been made in the field, all of which set plastids to become a centrepoint of future plant engineering efforts. The present review briefly describes ‘the state of the art’ of the technology along with its salient features whilst highlighting the latesttrends in the area of chloroplast transformation.
机译：成本飞涨，以及各行各业对重组蛋白的需求不断增长，促使人们寻求寻找更便宜，更安全并可以达到现代安全标准的替代生产方式。在这种情况下，植物正逐渐成为外来蛋白质的替代生产平台。叶绿体-具有内置的显着能力来高水平表达外源蛋白质的绿色质体-具有多种吸引人的功能，这使植物成为低成本大规模生产高价值目标的极有用的系统。因此，叶绿体的转化具有巨大的潜力，可以应对人口增长带来的食品，饲料和药品领域的挑战。该领域已经取得了许多进展，所有这些都使质体成为未来植物工程工作的重点。本综述简要介绍了该技术的“最新技术”及其显着特征，同时重点介绍了叶绿体转化领域的最新趋势。

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