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Association of immunologic thrombocytopenia and the Guillain-Barr茅 syndrome

机译:免疫性血小板减少症与吉兰-巴尔茅综合征的关联

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The immunologic thrombocytopenic purpura is an autoimmune, benign, of frequent appearance disease characterized by the presence of antibodies directed to glycoproteins of platelet membrane producing a decrease of platelet count and cutaneous-mucosal hemorrhagic manifestations. The Guillain-Barré syndrome is also a disease autoimmune by origin where the loss of immunological tolerance causes the appearance of antibodies directed to gangliosides of peripheral nerves. This is the case of female patient aged 40 diagnosed with a chronic immunologic thrombocytopenic purpura beginning with an ascendant motor paralysis, without respiratory compromise, facial paralysis and intense pain in dorsal and lumbar regions and also a diagnosis of Guillain-Barré syndrome with immediate treatment based on vitamin-therapy and high dose of steroids. After some months of follow-up and rehabilitation there was a satisfactory evolution with remission of all neurological symptoms.
机译:免疫性血小板减少性紫癜是一种自身免疫性,良性的,频繁出现的疾病,其特征在于存在针对血小板膜糖蛋白的抗体,从而导致血小板计数减少和皮肤粘膜出血表现减少。 Guillain-Barré综合征也是一种自身免疫性疾病,其免疫耐受性下降导致出现针对外周神经神经节苷脂的抗体。这是一名40岁的女性患者,被诊断出患有慢性免疫性血小板减少性紫癜,开始出现上升性运动麻痹,无呼吸功能减退,面部麻痹以及背部和腰部区域剧烈疼痛,并诊断为格林巴利综合征并立即治疗维生素治疗和高剂量的类固醇。经过几个月的随访和康复,所有神经系统症状均得到缓解,进展良好。

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