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The Impact of Non-Steroidal Anti-Inflammatory Agents after Phacoemulsification on Quality of Life: A Randomized Study

机译:超声乳化术后非甾体类消炎药对生活质量的影响:一项随机研究

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IntroductionThe purpose of our study was to investigate the impact of ketorolac addition to the well-established combination of antibiotic-steroid agent in terms of vision-related quality of life. MethodsPatients were randomized to: (1) fixed combination of tobramycin 0.3%–dexamethasone 0.1%, one drop qid ( n =?68) and (2) fixed combination of tobramycin 0.3%–dexamethasone 0.1%, one drop qid, plus ketorolac tromethamine 0.5%, one drop tid ( n =?70). All patients completed the VFQ-25 questionnaire to assess their functional vision before cataract surgery and postoperatively on days 7, 28 and 42. The statistical analysis comprised the point-wise comparison between the two groups at the four time points for all sub-scales of the VFQ-25 questionnaire, as well as the composite score. ResultsNo significant differences were noted regarding the composite score, as well as all subscales in all examined time points. ConclusionsThe addition of ketorolac did not seem to offer any additional benefit in terms of vision-related quality of life.
机译:引言我们研究的目的是从视力相关的生活质量方面,研究将酮咯酸添加到公认的抗生素-类固醇药物组合中的影响。方法将患者随机分为:(1)妥布霉素0.3%–地塞米松0.1%固定组合,一滴qid(n =?68)和(2)妥布霉素0.3%–地塞米松0.1%固定组合,一滴qid,加酮咯酸三甲胺0.5%,一滴tid(n =≤70)。所有患者均完成了VFQ-25调查问卷,以评估白内障手术前和术后第7、28和42天的功能视力。统计分析包括两组在四个时间点的所有子量表的逐点比较。 VFQ-25问卷以及综合评分。结果在所有检查的时间点上,综合评分以及所有子量表均未发现明显差异。结论添加酮咯酸似乎并没有提供与视力相关的生活质量方面的任何其他益处。

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