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首页> 外文期刊>Sri Lanka Journal of Psychiatry >Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study
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Estimation of serum zinc and copper levels patients with schizophrenia: a preliminary study

机译：精神分裂症患者血清锌和铜水平的估计：初步研究

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Introduction: Trace elements are essential for normal metabolism. Their dysregulation adversely affects biological processes and may play a role in the pathogenesis of various diseases including schizophrenia. The role of micronutrients in schizophrenia has been investigated in a limited number of studies; the results are inconclusive. Aims: To examine the serum levels of zinc and copper in patients with schizophrenia in comparison to healthy controls and also assess these levels in the acute and chronic stage of the illness Method: The study population comprised of 150 cases and 150 age-matched controls. Their serum zinc and copper levels were measured by an Atomic Absorption Spectrophotometer. Among the cases, the stage of illness was assessed using the Positive and Negative Syndrome Scale (PANSS) score. Results: The zinc and copper levels were higher significantly in patients with schizophrenia than in the control group. Conclusion: The evaluation of zinc and copper levels in patients with schizophrenia warrants further study.DOI: http://dx.doi.org/10.4038/sljpsyc.v5i1.7076 SL J Psychiatry 2014; 5 (1): 14-17
机译：简介：微量元素对于正常新陈代谢至关重要。它们的失调对生物学过程有不利影响，并可能在包括精神分裂症在内的各种疾病的发病机理中起作用。微量研究中已经研究了微量营养素在精神分裂症中的作用。结果尚无定论。目的：与健康对照相比，检查精神分裂症患者的血清锌和铜水平，并在疾病的急性和慢性阶段评估这些水平。方法：研究人群包括150例和150个年龄匹配的对照。用原子吸收分光光度计测量它们的血清锌和铜水平。在这些病例中，使用阳性和阴性综合征量表（PANSS）评分来评估疾病的阶段。结果：精神分裂症患者的锌和铜水平显着高于对照组。结论：对精神分裂症患者锌和铜水平的评估值得进一步研究。DOI：http://dx.doi.org/10.4038/sljpsyc.v5i1.7076 SL J Psychiatry 2014; 5（1）：14-17

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