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首页> 外文期刊>Journal of Behavioral and Brain Science >Chronic Headache after Pediatric Brain Injury: A Systematic Review
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Chronic Headache after Pediatric Brain Injury: A Systematic Review

机译：小儿脑损伤后的慢性头痛：系统评价

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Introduction: Chronic pain is an under-diagnosed consequence of traumatic brain injury (TBI) in subjects aged ≤16. The objective of this study was to determine its prevalence. Methods: The Ovid/Medline database was searched for articles published between 1951 and February 2008 using any combination of the terms brain injury, pain, headache, blast injury, and combat. The PubMed, MD Consult, Cochrane Collaboration, National Institutes of Health Clinical Trials Database, Meta-Register of Current Controlled Trials, and CRISP databases were searched using the keyword brain injury. 1110 articles were identified for evaluation. 258 articles were reviewed and 26 met the inclusion criteria for calculating the prevalence of chronic pain after TBI. Three cross-sectional studies met the inclusion criteria for calculating this prevalence in the population aged ≤16. Results: Twenty-six studies (18 cross-sectional, 5 prospective, and 3 retrospective) including 4468 patients with TBIs were identified. Fifteen studies assessed headache (HA) pain in 1932 patients. Of these, 1081 complained of chronic HA, yielding a prevalence of 56.0% (95%CI, 53.9% - 58.2%). Three studies furnished data on 262 patients with TBI and age ≤16. One-hundred-fifteen of these subjects experienced chronic HA suggesting prevalence of 43.9% (95%CI, 37.9% - 49.9%) in this population. We found evidence to suggest that there is an association between TBI and the development of chronic HA pain. Conclusions: Chronic pain from headache is a common complication of TBI and is common even among children with apparently minor injuries to the brain. The evidence suggests that this condition is independent of psychiatric disorders such as post-traumatic stress disorder and depression.
机译：简介：慢性疼痛是≤16岁受试者脑外伤（TBI）的不足诊断结果。这项研究的目的是确定其患病率。方法：搜索Ovid / Medline数据库中1951年至2008年2月之间使用脑损伤，疼痛，头痛，爆炸伤和战斗等术语的任意组合发表的文章。使用关键字“脑损伤”搜索了PubMed，MD Consult，Cochrane合作，美国国立卫生研究院临床试验数据库，当前对照试验的Meta-Register和CRISP数据库。确定了1110篇文章进行评估。回顾了258篇文章，其中26篇符合纳入标准，用于计算TBI后慢性疼痛的患病率。三项横断面研究均符合纳入标准，可计算≤16岁人口的患病率。结果：确定了26项研究（18项横断面研究，5项前瞻性研究和3项回顾性研究），包括4468例TBI患者。十五项研究评估了1932名患者的头痛（HA）疼痛。在这些患者中，有1081例患有慢性HA，患病率为56.0％（95％CI，53.9％-58.2％）。三项研究提供了262例TBI和≤16岁患者的数据。这些受试者中有十五十五名患有慢性HA，表明该人群的患病率为43.9％（95％CI，37.9％-49.9％）。我们发现证据表明，TBI与慢性HA疼痛的发展之间存在关联。结论：头痛引起的慢性疼痛是TBI的常见并发症，甚至在脑部轻度受伤的儿童中也很常见。有证据表明，这种情况与精神疾病无关，例如创伤后应激障碍和抑郁症。

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