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首页> 外文期刊>Journal of Young Pharmacists >Effects of Gamma Irradiation on Microbiological, Phytochemical Content, Antioxidant Activity and Inhibition of Angiotensin Converting Enzyme (ACE) Activity of Peperomia pellucida (L.) Kunth
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Effects of Gamma Irradiation on Microbiological, Phytochemical Content, Antioxidant Activity and Inhibition of Angiotensin Converting Enzyme (ACE) Activity of Peperomia pellucida (L.) Kunth

机译：伽玛射线辐照对白粉病菌微生物学，植物化学含量，抗氧化活性和血管紧张素转化酶（ACE）活性的抑制作用

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Objective: Gamma irradiation is an effective technique can be used to reduce contaminants in herbal products. Peperomia pellucida (L.) Kunth belongs to Piperaceae family has some biological activity, such as antioxidant and ACE inhibitor. The aimed of this research was to determine the effects of gamma irradiation on microbiological, phytochemical content, antioxidant and ACE inhibition activity. Methods: Sample was irradiated at a various dose of 0, 2.5, 5, 7.5 and 10 kGy. Microbiological was determined as total aerobic plate count (TAPC), and total yeast and mold (TYC), total phenolic content (TPC), total flavonoid content (TFC), antioxidant and ACE inhibition activity were investigated by various in vitro colorimetric methods. Results: Irradiation dose of 10 kGy reduced TAPC and TYC. Irradiation dose of 10 kGy slightly increased TPC, antioxidant, and ACE inhibition activity (p<0.05) but reduced TFC significantly (p<0,05) and caused degradation of flavonoids in this plant. Correlation analysis showed that phenolic compounds have a role as antioxidant and ACE inhibitor. Conclusion: gamma irradiation was found to be sufficient to ensure microbiological safety, increase TPC, the antioxidant and ACE inhibitory activity but caused degradation of flavonoids on Peperomia pellucida (L.) Kunth.
机译：目的：伽马射线辐照是一种有效的技术，可用于减少草药产品中的污染物。 Peperomia pellucida（L.）Kunth属于Piperaceae家族，具有一定的生物活性，例如抗氧化剂和ACE抑制剂。这项研究的目的是确定伽玛射线对微生物，植物化学成分，抗氧化剂和ACE抑制活性的影响。方法：以0、2.5、5、7.5和10 kGy的不同剂量照射样品。通过总需氧板数（TAPC）确定微生物，并通过各种体外比色法研究总酵母和霉菌（TYC），总酚含量（TPC），总黄酮含量（TFC），抗氧化剂和ACE抑制活性。结果：10 kGy的辐照剂量降低了TAPC和TYC。 10 kGy的辐照剂量略微增加了TPC，抗氧化剂和ACE抑制活性（p <0.05），但显着降低了TFC（p <0.05），并导致该植物中的类黄酮降解。相关分析表明，酚类化合物具有抗氧化剂和ACE抑制剂的作用。结论：发现γ射线足以确保微生物安全，增加TPC，抗氧化剂和ACE抑制活性，但会导致Peperomia pellucida（L.）Kunth上的类黄酮降解。

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