The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes.

H S Ro; D A Roncari

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The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes.

机译：C / EBP结合区和相邻位点调节人脂肪细胞中脂肪P2基因的表达。

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Human preadipocytes contain nuclear factors that specifically bind to the AE-1 sequence, previously demonstrated as an enhancer element in the regulation of adipose P2 gene expression during 3T3 adipose differentiation. By transient transfection and in vivo competition experiments, the trans-acting factors were found to bind either to the C/EBP recognition site in the AE-1 sequence and act as a negative regulator or to the adjacent site (termed 3' AE-1) and act as a positive regulator of adipose P2 gene activity in human preadipocytes.

机译：人前脂肪细胞含有与AE-1序列特异性结合的核因子，该因子先前在3T3脂肪分化过程中被证明是调控脂肪P2基因表达的增强子。通过瞬时转染和体内竞争实验，发现反式作用因子与AE-1序列中的C / EBP识别位点结合并充当负调节剂或与邻近位点（称为3'AE-1）结合）并在人类前脂肪细胞中充当脂肪P2基因活性的正向调节剂。

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《Molecular and Cellular Biology》 |1991年第4期|共4页
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H S Ro; D A Roncari;
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中图分类细胞生物学;
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6. The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes. [O] . H S Ro, D A Roncari 1991

机译：C / EBP结合区和相邻位点调节人脂肪细胞中脂肪P2基因的表达。
7. The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes. [O] . Ro, H S, Roncari, D A 1991

机译：C / EBP结合区和相邻位点调节人脂肪细胞中脂肪P2基因的表达。

The C/EBP-binding region and adjacent sites regulate expression of the adipose P2 gene in human preadipocytes.

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