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The use of meta-analytical tools in risk assessment for food safety

机译：在食品安全风险评估中使用荟萃分析工具

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摘要

This communication deals with the use of meta-analysis as a valuable tool for the synthesis of food safety research, and in quantitative risk assessment modelling. A common methodology for the conduction of meta-analysis (i.e., systematic review and data extraction, parameterisation of effect size, estimation of overall effect size, assessment of heterogeneity, and presentation of results) is explained by reviewing two meta-analyses derived from separate sets of primary studies of Salmonella in pork. Integrating different primary studies, the first meta-analysis elucidated for the first time a relationship between the proportion of Salmonella-carrier slaughter pigs entering the slaughter lines and the resulting proportion of contaminated carcasses at the point of evisceration; finding that the individual studies on their own could not reveal. On the other hand, the second application showed that meta-analysis can be used to estimate the overall effect of a critical process stage (chilling) on the incidence of the pathogen under study. The derivation of a relationship between variables and a probabilistic distribution is illustrations of the valuable quantitative information synthesised by the meta-analytical tools, which can be incorpo rated in risk assessment modelling. Strengths and weaknesses of meta-analysis within the context of food safety are also discussed.
机译：此次交流涉及使用荟萃分析作为食品安全研究综合和定量风险评估建模中的宝贵工具。进行荟萃分析的通用方法（即系统综述和数据提取，效应大小的参数化，总体效应大小的估计，异质性评估和结果展示）通过回顾两个分别源自不同领域的荟萃分析进行了解释猪肉沙门氏菌的初步研究。结合不同的基础研究，第一个荟萃分析首次阐明了进入屠宰线的沙门氏菌携带的屠宰猪的比例与在内脏点所产生的car体污染比例之间的关系。发现单独的研究无法揭示。另一方面，第二项申请显示，荟萃分析可用于评估关键过程阶段（冷却）对所研究病原体发生率的总体影响。变量与概率分布之间关系的推导是由荟萃分析工具合成的有价值的定量信息的说明，可以将其纳入风险评估建模中。还讨论了在食品安全范围内进行荟萃分析的优缺点。

著录项

  • 来源
    《Food microbiology》 |2011年第4期|p.823-827|共5页
  • 作者

    Ursula Gonzales-Barron; Francis Butler;

  • 作者单位

    Biosystems Engineering, UCD School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Dublin 4, Ireland;

    Biosystems Engineering, UCD School of Agriculture, Food Science and Veterinary Medicine, University College Dublin, Dublin 4, Ireland;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Meta-analysis; Risk assessment; Salmonella; Slaughter; pig; Pork; Chilling;

    机译：荟萃分析;风险评估;沙门氏菌;屠宰;猪;猪肉;低温;

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