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首页> 外文期刊>Biomedical Circuits and Systems, IEEE Transactions on >Fault Modeling and Functional Test Methods for Digital Microfluidic Biochips
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Fault Modeling and Functional Test Methods for Digital Microfluidic Biochips

机译：数字微流控生物芯片的故障建模和功能测试方法

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摘要

Dependability is an important attribute for microfluidic biochips that are used for safety-critical applications, such as point-of-care health assessment, air-quality monitoring, and food-safety testing. Therefore, these devices must be adequately tested after manufacture and during bioassay operations. Known techniques for biochip testing are all function oblivious (i.e., while they can detect and locate defect sites on a microfluidic array, they cannot be used to ensure correct operation of functional units). In this paper, we introduce the concept of functional testing of microfluidic biochips. We address fundamental biochip operations, such as droplet dispensing, droplet transportation, mixing, splitting, and capacitive sensing. Long electrode actuation times are avoided to ensure that there is no electrode degradation during testing. The functional testing of pin-constrained biochips is also studied. We evaluate the proposed test methods using simulations as well as experiments for a fabricated biochip.
机译：可靠性是用于安全关键型应用的微流体生物芯片的重要属性，例如护理点健康评估，空气质量监测和食品安全性测试。因此，必须在制造后和生物测定操作期间对这些设备进行充分的测试。用于生物芯片测试的已知技术都是功能不明确的（即，尽管它们可以检测和定位微流体阵列上的缺陷部位，但不能用于确保功能单元的正确操作）。在本文中，我们介绍了微流控生物芯片功能测试的概念。我们致力于生物芯片的基本操作，例如液滴分配，液滴运输，混合，分离和电容式传感。避免较长的电极启动时间，以确保在测试过程中电极不会退化。还研究了引脚受限的生物芯片的功能测试。我们使用模拟以及人造生物芯片的实验评估提出的测试方法。

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